• 30 kwietnia, 2021
bodiesrevealed

Strukturalny wpływ glikodendrymerów rekrutujących

Strukturalny wpływ glikodendrymerów rekrutujących przeciwciała (ARG) na cytotoksyczność przeciwnowotworową 

  • The recruitment of endogenous antibodies towards most cancers cells has develop into a dependable antitumoral immunotherapeutic various over the past decade. The covalent attachment of antibody and tumor binding modules (ABM and TBM) inside a single, well-defined artificial molecule was certainly demonstrated to advertise the formation of an interacting ternary advanced between each the antibodies and the focused cell, which often ends in the simultaneous immune-mediated mobile destruction.
  • In a preliminary examine, now we have described the primary Antibody Recruiting Glycodendrimers (ARGs), combining cRGD as ligands for the αVβ3-expressing melanoma cell line M21 and Rha as ligand for pure IgM, and demonstrated that multivalency is an important requirement to kind this advanced. Within the current examine, we synthesized a brand new sequence of ARGs composed of ABMs, i.e. self-condensed rhamnosylated cyclopeptide and polylysine dendrimer, which have been conjugated to the TBM with or with out spacer.
  • Circulate cytometry and confocal microscopy experiments with human serum and completely different cell traces revealed that the ABM geometry considerably influences the ternary advanced formation in M21, whereas no important binding happens in BT 549 having low integrin expression. As well as, we exhibit with a mobile viability assay that ARGs induce excessive degree of cytotoxicity towards M21 which can also be in shut correlation with the ABM construction.
  • Particularly, now we have proven that ARG combining cyclopeptide core and branches, with or with out spacer, induce 40-57% of selective cytotoxicity towards M21 cells within the presence of human serum because the distinctive supply of immunity effectors. Lastly, we additionally spotlight that the spacer between ABM and TBM permits a rise of the immune-mediate cytotoxicity even with ABM of decrease valency.
bodiesrevealed
bodiesrevealed

Anti-LAMP3 antibody (Alexa-fluor 546)

STJ170005 100 µg
EUR 471.6
Description: The dendritic cell lysosomal-associated membrane protein (DC-LAMP)/CD208 is a type I integral transmembrane glycoprotein mostly homologous to CD68, of about 45 kDa in mouse and 90 kDa in human (glycosylation), with a bipartite C-terminal structure divided by a serine/proline rich region, a transmembrane domain and a conserved tyrosine-based lysosomal targeting motif in its cytoplasmic tail. Initially cloned as a specific marker of human mature dendritic cells (DCs), DC-LAMP has been subsequently shown to be expressed in alveolar type II pneumocytes. In both cell types, the molecule is found in the limiting membrane of intracellular multi-lamellar bodies, known as MIIC (MHC class II compartments) in human mature DCs and as lung surfactant-containing lamellar bodies in type II pneumocytes. In the latter cell type, DC-LAMP expression is also detected at the cell surface.

Anti-LAMP3 antibody (Alexa-fluor 647)

STJ170006 100 µg
EUR 471.6
Description: The dendritic cell lysosomal-associated membrane protein (DC-LAMP)/CD208 is a type I integral transmembrane glycoprotein mostly homologous to CD68, of about 45 kDa in mouse and 90 kDa in human (glycosylation), with a bipartite C-terminal structure divided by a serine/proline rich region, a transmembrane domain and a conserved tyrosine-based lysosomal targeting motif in its cytoplasmic tail. Initially cloned as a specific marker of human mature dendritic cells (DCs), DC-LAMP has been subsequently shown to be expressed in alveolar type II pneumocytes. In both cell types, the molecule is found in the limiting membrane of intracellular multi-lamellar bodies, known as MIIC (MHC class II compartments) in human mature DCs and as lung surfactant-containing lamellar bodies in type II pneumocytes. In the latter cell type, DC-LAMP expression is also detected at the cell surface.

Anti-IL3RA antibody (Alexa-fluor 488)

STJ170009 100 µg
EUR 471.6
Description: IL3 exerts its biologic activity through its interaction with a cell surface receptor that consists of two subunits. The a subunit (CD123) specifically binds IL3, whereas the ß subunit is required for signaling and is common to the GMCSFR and IL5-R. 107D2.08 and 106C2.02 mAbs were obtained after mouse immunization with sorted human tonsillar PDC. Both clones strongly stain PDCs and basophils, weakly stain monocytes, CD34+ derived DCs and CD11c+ DC, while no staining is observed on T, B, NK cells as well as on mono-derived DCs. Staining with 107D2.08 and 106C2.02 mAbs are maintained on sorted PDC cultured in the presence of IL3 and CD40L, but lost when IL3 alone is added to the culture. The recognition of the IL3Ra chain by 107D2.08 and 106C2.02 was confirmed by transfection studies. 107D2.08 appeared to be the most appropriate clone for in situ studies. 107D2.08 allowed the first observation of IL3Ra+ cells in breast tumor microenvironment

Anti-IL3RA antibody (Alexa-fluor 546)

STJ170010 100 µg
EUR 471.6
Description: IL3 exerts its biologic activity through its interaction with a cell surface receptor that consists of two subunits. The a subunit (CD123) specifically binds IL3, whereas the ß subunit is required for signaling and is common to the GMCSFR and IL5-R. 107D2.08 and 106C2.02 mAbs were obtained after mouse immunization with sorted human tonsillar PDC. Both clones strongly stain PDCs and basophils, weakly stain monocytes, CD34+ derived DCs and CD11c+ DC, while no staining is observed on T, B, NK cells as well as on mono-derived DCs. Staining with 107D2.08 and 106C2.02 mAbs are maintained on sorted PDC cultured in the presence of IL3 and CD40L, but lost when IL3 alone is added to the culture. The recognition of the IL3Ra chain by 107D2.08 and 106C2.02 was confirmed by transfection studies. 107D2.08 appeared to be the most appropriate clone for in situ studies. 107D2.08 allowed the first observation of IL3Ra+ cells in breast tumor microenvironment

Anti-IL3RA antibody (Alexa-fluor 647)

STJ170011 100 µg
EUR 471.6
Description: IL3 exerts its biologic activity through its interaction with a cell surface receptor that consists of two subunits. The a subunit (CD123) specifically binds IL3, whereas the ß subunit is required for signaling and is common to the GMCSFR and IL5-R. 107D2.08 and 106C2.02 mAbs were obtained after mouse immunization with sorted human tonsillar PDC. Both clones strongly stain PDCs and basophils, weakly stain monocytes, CD34+ derived DCs and CD11c+ DC, while no staining is observed on T, B, NK cells as well as on mono-derived DCs. Staining with 107D2.08 and 106C2.02 mAbs are maintained on sorted PDC cultured in the presence of IL3 and CD40L, but lost when IL3 alone is added to the culture. The recognition of the IL3Ra chain by 107D2.08 and 106C2.02 was confirmed by transfection studies. 107D2.08 appeared to be the most appropriate clone for in situ studies. 107D2.08 allowed the first observation of IL3Ra+ cells in breast tumor microenvironment

Anti-CD207 antibody (Alexa-fluor 488)

STJ170014 100 µg
EUR 471.6
Description: Langerin/CD207 is a transmembrane C-type lectin receptor (CLR) of epidermal and mucosal Langerhans cells (LCs) that induces Birbeck's granule formation. Langerin features a single carbohydrate recognition domain (CRD) with mannose-type specificity in its extracellular portion. Langerin is unique among the CLRs in that it contains an intracellular domain with a proline-rich motif. Langerin expression has not been reported outside the DC system. (Valladeau J et al, 1999, Eur.J.Immunol., 29:2695-2704; Valladeau J et al, 2000 Immunity, 12 : 71-81; Kashihara M et al, 1986, J.Invest.Derm., 87 :602-607 Ito T et al, 1999, J.Immunol., 163 :1409-1419 ;Saeland S & Valladeau J, CD207 (Langerin) Workshop reports 2002, Leukocyte-Typing VII, White Cell Diff Antigens, D. Mason et al, Eds, Oxford University Press:306-307)

Anti-CD207 antibody (Alexa-fluor 546)

STJ170015 100 µg
EUR 471.6
Description: Langerin/CD207 is a transmembrane C-type lectin receptor (CLR) of epidermal and mucosal Langerhans cells (LCs) that induces Birbeck's granule formation. Langerin features a single carbohydrate recognition domain (CRD) with mannose-type specificity in its extracellular portion. Langerin is unique among the CLRs in that it contains an intracellular domain with a proline-rich motif. Langerin expression has not been reported outside the DC system. (Valladeau J et al, 1999, Eur.J.Immunol., 29:2695-2704; Valladeau J et al, 2000 Immunity, 12 : 71-81; Kashihara M et al, 1986, J.Invest.Derm., 87 :602-607 Ito T et al, 1999, J.Immunol., 163 :1409-1419 ;Saeland S & Valladeau J, CD207 (Langerin) Workshop reports 2002, Leukocyte-Typing VII, White Cell Diff Antigens, D. Mason et al, Eds, Oxford University Press:306-307)

Anti-CD207 antibody (Alexa-fluor 647)

STJ170016 100 µg
EUR 471.6
Description: Langerin/CD207 is a transmembrane C-type lectin receptor (CLR) of epidermal and mucosal Langerhans cells (LCs) that induces Birbeck's granule formation. Langerin features a single carbohydrate recognition domain (CRD) with mannose-type specificity in its extracellular portion. Langerin is unique among the CLRs in that it contains an intracellular domain with a proline-rich motif. Langerin expression has not been reported outside the DC system. (Valladeau J et al, 1999, Eur.J.Immunol., 29:2695-2704; Valladeau J et al, 2000 Immunity, 12 : 71-81; Kashihara M et al, 1986, J.Invest.Derm., 87 :602-607 Ito T et al, 1999, J.Immunol., 163 :1409-1419 ;Saeland S & Valladeau J, CD207 (Langerin) Workshop reports 2002, Leukocyte-Typing VII, White Cell Diff Antigens, D. Mason et al, Eds, Oxford University Press:306-307)

Anti-IL7R antibody (Alexa-fluor 488)

STJ170020 100 µg
EUR 471.6
Description: The IL7-R consists of 2 chains, IL-7R known as CD127 and common cytokine receptor chain known as CD132. A 75 to 80kDa human IL-7 receptor has been cloned that belongs to hematopoietic cytokinereceptor super family. R34-34, raised against human leukemic pre-B cells, recognized a molecule expressed on normal B cell precursors but not on mature B cells. This antibody specifically reverted IL-7 mediated growth inhibition of leukemic BCP (normal B cells precursors) and mature T cells. IL-7R expression is dramatically influenced by cytokines and antigens. This IL-7R displays both high and low affinity for its ligand (IL-7). Inhibitory and proliferative effects of IL-7 can be mediated through the same receptor on various lineages. CD4+ memory T cells express high level of IL-7R Subsets that express it generally require it, including progenitors of T and B cells, naïve and memory T cells. (Pandrau-Garcia D et al, 1994, Blood, 83, 3613-9 Mazzucchelli R et al, Nat. Review Immunol., 2007,7, 144-54)

Anti-IL7R antibody (Alexa-fluor 546)

STJ170021 100 µg
EUR 471.6
Description: The IL7-R consists of 2 chains, IL-7R known as CD127 and common cytokine receptor chain known as CD132. A 75 to 80kDa human IL-7 receptor has been cloned that belongs to hematopoietic cytokinereceptor super family. R34-34, raised against human leukemic pre-B cells, recognized a molecule expressed on normal B cell precursors but not on mature B cells. This antibody specifically reverted IL-7 mediated growth inhibition of leukemic BCP (normal B cells precursors) and mature T cells. IL-7R expression is dramatically influenced by cytokines and antigens. This IL-7R displays both high and low affinity for its ligand (IL-7). Inhibitory and proliferative effects of IL-7 can be mediated through the same receptor on various lineages. CD4+ memory T cells express high level of IL-7R Subsets that express it generally require it, including progenitors of T and B cells, naïve and memory T cells. (Pandrau-Garcia D et al, 1994, Blood, 83, 3613-9 Mazzucchelli R et al, Nat. Review Immunol., 2007,7, 144-54)

Anti-IL7R antibody (Alexa-fluor 647)

STJ170022 100 µg
EUR 471.6
Description: The IL7-R consists of 2 chains, IL-7R known as CD127 and common cytokine receptor chain known as CD132. A 75 to 80kDa human IL-7 receptor has been cloned that belongs to hematopoietic cytokinereceptor super family. R34-34, raised against human leukemic pre-B cells, recognized a molecule expressed on normal B cell precursors but not on mature B cells. This antibody specifically reverted IL-7 mediated growth inhibition of leukemic BCP (normal B cells precursors) and mature T cells. IL-7R expression is dramatically influenced by cytokines and antigens. This IL-7R displays both high and low affinity for its ligand (IL-7). Inhibitory and proliferative effects of IL-7 can be mediated through the same receptor on various lineages. CD4+ memory T cells express high level of IL-7R Subsets that express it generally require it, including progenitors of T and B cells, naïve and memory T cells. (Pandrau-Garcia D et al, 1994, Blood, 83, 3613-9 Mazzucchelli R et al, Nat. Review Immunol., 2007,7, 144-54)

SAM FCM (Alexa Fluor 647)

abx098902-100tests 100 tests
EUR 1479.6

SAM FCM (Alexa Fluor 488)

abx098904-60tests 60 tests
EUR 1629.6

Anti-RPSA Alexa Fluor® 488

A4-829-C100 0.1 mg
EUR 372

Goat anti Mouse IgG1 (Alexa Fluor 488)

43R-1649 500 ug
EUR 684
Description: Goat anti Mouse IgG1 secondary antibody (Alexa Fluor 488)

Anti-Hu CD16 Alexa Fluor® 488

A4-646-T100 100 tests
EUR 322.8

Alpha Fluor™ 488 acid [equivalent to Alexa Fluor™ 488 acid]

1790 5 mg
EUR 367.2

Alpha Fluor™ 532 acid [equivalent to Alexa Fluor™ 532 acid]

1795 10 mg
EUR 471.6

HAPLN2 antibody

70R-9514 50 ug
EUR 560.4
Description: Affinity purified rabbit polyclonal HAPLN2 antibody

Mouse IgG1-Alexa 555 conjugate (isotype control)

20102-101-A555 50 Tests
EUR 315.6

Donkey anti Goat IgG (H + L) (Alexa Fluor 594)

43R-ID005AF 500 ug
EUR 405.6
Description: Donkey anti Goat IgG (H + L) secondary antibody (Alexa Fluor 594)

Donkey anti Rat IgG (H + L) (Alexa Fluor 594)

43R-ID022AF 500 ug
EUR 436.8
Description: Donkey anti Rat IgG (H + L) secondary antibody (Alexa Fluor 594)

Donkey anti Goat IgG (H + L) (Alexa Fluor 647)

43R-ID028AF 500 ug
EUR 516
Description: Donkey anti Goat IgG (H + L) secondary antibody (Alexa Fluor 647)

Donkey anti Rat IgG (H + L) (Alexa Fluor 594)

43R-ID047AF 500 ug
EUR 554.4
Description: Donkey anti Rat IgG (H + L) secondary antibody (Alexa Fluor 594)

Donkey anti Chicken IgY (H + L) (Alexa Fluor 594)

43R-ID056AF 500 ug
EUR 411.6
Description: Donkey anti Chicken IgY secondary antibody (H + L) (Alexa Fluor 594)

Donkey anti Chicken IgY (H + L) (Alexa Fluor 647)

43R-ID060AF 300 ug
EUR 510
Description: Donkey anti Chicken IgY (H + L) (Fab'2) (Alexa Fluor 647)

Rabbit anti Chicken IgY (H + L) (Alexa Fluor 594)

43R-IR016AF 1 mg
EUR 337.2
Description: Rabbit anti Chicken IgY (H + L) secondary antibody (Alexa Fluor 594)

AF350-streptavidin conjugate [Streptavidin, Alexa Fluor™ 350 Conjugate]

16890 1 mg
EUR 211.2

AF488-streptavidin conjugate [Streptavidin, Alexa Fluor™ 488 Conjugate]

16891 1 mg
EUR 211.2

AF594-streptavidin conjugate [Streptavidin, Alexa Fluor™ 594 Conjugate]

16892 1 mg
EUR 211.2

AF350 Phalloidin [equivalent to Alexa Fluor® 350 phalloidin]

23150 300 Tests
EUR 367.2

AF488 Phalloidin [equivalent to Alexa Fluor® 488 phalloidin]

23153 300 Tests
EUR 367.2

AF594 Phalloidin [equivalent to Alexa Fluor® 594 phalloidin]

23158 300 Tests
EUR 367.2

Anti-Hu CD72 Alexa Fluor® 488

A4-310-T100 100 tests
EUR 322.8

Anti-Bov CD9 Alexa Fluor® 488

A4-354-C100 0.1 mg
EUR 322.8

Anti-Hu CD30 Alexa Fluor® 700

A7-455-T100 100 tests
EUR 322.8

Anti-Hu CD94 Alexa Fluor® 700

A7-727-T100 100 tests
EUR 322.8

Anti-Hu CD56 Alexa Fluor® 700

A7-789-T100 100 tests
EUR 322.8

Hapln2/ Rat Hapln2 ELISA Kit

ELI-31484r 96 Tests
EUR 1063.2

Anti-LAMP3 (human) Monoclonal Antibody (104G4) (Alexa Fluor® 488)

M09406 100ug
EUR 678
Description: Mouse Monoclonal LAMP3 (human) Antibody (104G4) (Alexa Fluor® 488). Validated in IHC and tested in Human.

Donkey anti Goat IgG (H + L) (Fab 2) (Alexa Fluor 594)

43R-ID012AF 300 ug
EUR 492
Description: Donkey anti Goat IgG (H + L) secondary antibody (Fab'2) (Alexa Fluor 594)

Anti-Hu CD3 zeta (pY153) Alexa Fluor® 488

A4-686-C100 0.1 mg
EUR 322.8

Anti-Hu CD3 zeta (pY72) Alexa Fluor® 488

A4-712-C100 0.1 mg
EUR 322.8

Anti-Hu CD3 zeta (pY142) Alexa Fluor® 488

A4-730-C100 0.1 mg
EUR 322.8

Anti-Hu CD3 zeta (pY111) Alexa Fluor® 488

A4-737-C100 0.1 mg
EUR 322.8

Donkey Anti-Goat IgG (H+L), Alexa Fluor® 594 Conjugated

Ab8011-001 1mg
EUR 400.8

Donkey Anti-Rabbit IgG (H+L), Alexa Fluor® 488 Conjugated

Ab8032-001 0.5mg
EUR 522

Anti-Hu CD3 zeta (pY153) Alexa Fluor® 647

A6-686-C100 0.1 mg
EUR 322.8

Anti-Hu CD3 zeta (pY72) Alexa Fluor® 647

A6-712-C100 0.1 mg
EUR 322.8

Anti-Hu CD3 zeta (pY142) Alexa Fluor® 647

A6-730-C100 0.1 mg
EUR 322.8

Anti-Hu CD3 zeta (pY111) Alexa Fluor® 647

A6-737-C100 0.1 mg
EUR 322.8

Anti-Langerin (human) Monoclonal Antibody (DCGM4/122D5) (Alexa Fluor® 488)

M02316 100ug
EUR 696
Description: Mouse Monoclonal Langerin (human) Antibody (DCGM4/122D5) (Alexa Fluor® 488). Validated in IHC and tested in Human.

HAPLN2 siRNA

20-abx902412
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

HAPLN2 siRNA

20-abx919075
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

HAPLN2 siRNA

20-abx919076
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

anti-HAPLN2

YF-PA26528 50 ul
EUR 400.8
Description: Mouse polyclonal to HAPLN2

HAPLN2 Blocking Peptide

33R-4857 100 ug
EUR 216
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of HAPLN2 antibody, catalog no. 70R-9514

Rabbit Anti-Rat IgG (H+L)-Alexa 488 Fluor conjugate (adsorbed with human IgG)

50336 0.5 ml
EUR 270

Rabbit Anti-Rat IgG (H+L)-Alexa 594 Fluor conjugate (adsorbed with human IgG)

50337 0.5 ml
EUR 270

Mouse HAPLN2 shRNA Plasmid

20-abx978045
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Human HAPLN2 shRNA Plasmid

20-abx961797
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Rat HAPLN2 shRNA Plasmid

20-abx986153
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Mouse Hapln2 ELISA KIT

ELI-20847m 96 Tests
EUR 1038

Human HAPLN2 ELISA KIT

ELI-13081h 96 Tests
EUR 988.8

HAPLN2 Recombinant Protein (Rat)

RP204194 100 ug Ask for price

pCMV-SPORT6-HAPLN2 Plasmid

PVT16540 2 ug
EUR 390

HAPLN2 Recombinant Protein (Human)

RP061683 100 ug Ask for price

HAPLN2 Recombinant Protein (Mouse)

RP140915 100 ug Ask for price

Hapln2 ORF Vector (Rat) (pORF)

ORF068066 1.0 ug DNA
EUR 607.2

HAPLN2 ORF Vector (Human) (pORF)

ORF020562 1.0 ug DNA
EUR 486

Hapln2 ORF Vector (Mouse) (pORF)

ORF046973 1.0 ug DNA
EUR 607.2

AG 555

B6377-10 10 mg
EUR 172.8
Description: AG 555 is a potent and selective inhibitor of EGFR with IC50 value of 0.7 ?M. The epidermal growth factor receptor (EGFR) is the cell-surface receptor for epidermal growth factor and plays an important role in tumor invasion and cancer cell proliferation.

AG 555

B6377-25 25 mg
EUR 331.2
Description: AG 555 is a potent and selective inhibitor of EGFR with IC50 value of 0.7 ?M. The epidermal growth factor receptor (EGFR) is the cell-surface receptor for epidermal growth factor and plays an important role in tumor invasion and cancer cell proliferation.

AG 555

B6377-50 50 mg
EUR 536.4
Description: AG 555 is a potent and selective inhibitor of EGFR with IC50 value of 0.7 ?M. The epidermal growth factor receptor (EGFR) is the cell-surface receptor for epidermal growth factor and plays an important role in tumor invasion and cancer cell proliferation.

MCC-555

C4892-1 1 mg
EUR 189.6
Description: MCC-555, also known as RWJ-241947, is a novel peroxisome proliferator?activated receptor ? ligand [1]. The PPAR? receptors mainly express in adipose tissue, colon and macrophages involved in regulating fatty acid storage and glucose metabolism.

MCC-555

C4892-10 10 mg
EUR 1101.6
Description: MCC-555, also known as RWJ-241947, is a novel peroxisome proliferator?activated receptor ? ligand [1]. The PPAR? receptors mainly express in adipose tissue, colon and macrophages involved in regulating fatty acid storage and glucose metabolism.

MCC-555

C4892-5 5 mg
EUR 645.6
Description: MCC-555, also known as RWJ-241947, is a novel peroxisome proliferator?activated receptor ? ligand [1]. The PPAR? receptors mainly express in adipose tissue, colon and macrophages involved in regulating fatty acid storage and glucose metabolism.

AG 555

HY-15336 10mM/1mL
EUR 151.2

Anti-Cytokeratins Alexa Fluor488

A4-108-C025 0.025 mg
EUR 210

Anti-Cytokeratins Alexa Fluor488

A4-108-C100 0.1 mg
EUR 372

Anti-PSMA Alexa Fluor488

A4-539-C025 0.025 mg
EUR 272.4

Anti-PSMA Alexa Fluor488

A4-539-C100 0.1 mg
EUR 496.8

Anti-FoxP3 Alexa Fluor488

A4-601-C025 0.025 mg
EUR 241.2

Anti-FoxP3 Alexa Fluor488

A4-601-C100 0.1 mg
EUR 434.4

Anti-Phosphotyrosine Alexa Fluor647

A6-263-C025 0.025 mg
EUR 184.8

Anti-Phosphotyrosine Alexa Fluor647

A6-263-C100 0.1 mg
EUR 322.8

Anti-LCK Alexa Fluor647

A6-269-C025 0.025 mg
EUR 247.2

Anti-LCK Alexa Fluor647

A6-269-C100 0.1 mg
EUR 447.6

Anti-FoxP3 Alexa Fluor647

A6-601-C025 0.025 mg
EUR 241.2

Anti-FoxP3 Alexa Fluor647

A6-601-C100 0.1 mg
EUR 434.4

Influenza A (Swine H1N1) Hemagglutinin (A/California/14/2009) Peptide

11-555 0.05 mg
EUR 632.4
Description: Influenza A (Swine H1N1) Hemagglutinin (A/California/14/2009) Peptide

G-CSF Recombinant Protein

40-555 0.01 mg
EUR 481.2
Description: G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and murine G-CSF are cross-species reactive. Recombinant human G-CSF is an 18.7 kDa protein consisting of 174 amino acid residues.

IL-10 Recombinant Protein

90-555 10 ug
EUR 500.1
Description: Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells, B cells, keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells, natural killer cells and monocytes/macrophages. Several studies have suggested the potential application of IL-10 as an anti-inflammatory agent in the treatment of septic shock and as an immunosuppressive agent in certain T cell mediated autoimmune diseases.

Vanin-2 Recombinant Protein

91-555 0.05 mg
EUR 651.3
Description: Vascular Non-Inflammatory Molecule 2 (VNN2) is a member of the CN hydrolase family. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. they possess pantetheinase activity, which may play a role in oxidative-stress response. VNN2 is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. VNN2 involved in the thymus homing of bone marrow cells. In addition, VNN2 may regulate beta-2 integrin-mediated cell adhesion, migration and motility of neutrophil.

OX40 Recombinant Protein

92-555 0.05 mg
EUR 537.9
Description: OX40, also termed CD134 and TNFRSF4, is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis of effector and memory T cells. OX40 is expressed on CD4+ and CD8+ T cells upon engagement of the TCR by antigen presenting cells along with co-stimulation by CD40-CD40 Ligand and CD28-B7. The interaction between OX40 and OX40 ligand (OX40L) will occur when activated T cells bind to professional antigen-presenting cells (APCs). The T-cell functions, including cytokine production, expansion, and survival, are then enhanced by the OX40 costimulatory signals. OX40 signals are critical for controlling the function and differentiation of Foxp3+ regulatory T cells. OX40-OX40L interaction regulates T-cell tolerance, peripheral T-cell homeostasis, and T-cell-mediated inflammatory diseases.

IL12 B Recombinant Protein

96-555 0.02 mg
EUR 468.6
Description: Interleukin-12 (IL12) is also known as natural killer cell stimulatory factor (NKSF), cytotoxic lymphocyte maturation factor (CLMF) , is a heterodimeric cytokine encoded by two separate genes, IL-12A (p35) and IL-12B (p40). IL12 is naturally produced by dendritic cells, macrophages and human B-lymphoblastoid cells (NC-37) in response to antigenic stimulation. IL-12 is involved in the differentiation of naive T cells into Th0 cells and plays an important role in the activities of natural killer cells and T lymphocytes.IL-12 also has anti-angiogenic activity, which means it can block the formation of new blood vessels.Interleukin-12 subunit beta (IL12B) also known as NKSF2, CLMF2 and P40. Interleukin-12 subunit beta has been shown to interact with IL23. A large excess of monomeric IL12B is also secreted by the cells producing IL12, and exhibits no demonstrable biological activity. Overexpression of IL12B gene has been shown to be associated with the pathogenesis of multiple sclerosis. In addition, studies have revealed that the promoter polymorphism of this gene is implicated in the severity of atopic and non-atopic asthma in children.

Recombinant (E.Coli, His-tag) HIV-1 pol Integrase

RP-555 10 ug
EUR 196.8

Hapln2 sgRNA CRISPR Lentivector set (Rat)

K6955701 3 x 1.0 ug
EUR 406.8

HAPLN2 sgRNA CRISPR Lentivector set (Human)

K0928901 3 x 1.0 ug
EUR 406.8

Hapln2 sgRNA CRISPR Lentivector set (Mouse)

K3546001 3 x 1.0 ug
EUR 406.8

ICELISA na bazie przeciwciał monoklonalnych do badania przesiewowego diazynonu w próbkach warzyw 

Diazinon (DAZ) is an organophosphorus pesticide (OP), which is often used to stop and management dangerous pests that endanger agricultural merchandise. On this examine, we developed a novel heterology coating technique for the immunoassay of DAZ. The DAZ coating hapten might be immediately conjugated to the provider protein with out requiring a spacer arm. This proposed hapten coating technique is time-saving and considerably improves the sensitivity of the immunoassay because of the lack of a spacer arm. The as-synthesized coating antigen was used to display screen the monoclonal antibody (mAb).

Lastly, the developed oblique aggressive enzyme-linked immunoassay (icELISA) confirmed IC50 and restrict of detection (LOD) values of 0.58 ng mL-1 and eight pg mL-1, respectively. This methodology exhibited negligible cross-reactivity in direction of different analogues, and the recoveries of samples (cucumber, cabbage, and lettuce) ranged from 92.6% to 125.4%, with coefficients of variance (CV) beneath 12%. Good correlation between icELISA and high-performance liquid chromatography mass spectrometry (HPLC-MS/MS) was obtained. The proposed icELISA was a super instrument for monitoring DAZ residues in meals samples.

Odpowiedni środek utrwalający do barwienia MEM-G / 9 hodowanych ludzkich komórek nowotworowych trofoblastów JEG-Three HLA-G-dodatnich 

Human leukocyte antigen (HLA-G) participates in immunosuppression and is beneficial for prenatal diagnostics. Isolation of fetal cells optimistic for HLA-G by HLA-G antibody conjugated nanoparticles from the cervix of pregnant girls is the idea for non-invasive prenatal testing. Endocervical specimens are mounted in transport medium earlier than isolation utilizing antibody conjugated nanoparticles. Staining of HLA-G utilizing MEM-G/9 antibody, nonetheless, is restricted to unfixed cells. We investigated the impact of a number of fixatives on the interplay of HLA-G with MEM-G/9 within the HLA-G-positive cell line, JEG-3. We investigated absolute methanol, 1:1 acetate buffer:methanol, Pap answer and paraformaldehyde.

The results of those fixatives had been evaluated utilizing immunofluorescence. We discovered no MEM-G/9 floor staining of methanol mounted cells. Roughly 40% of JEG-Three cells mounted with paraformaldehyde didn’t stain. Almost all cells had been stained with MEM-G/9 following fixation with acetate buffer:methanol or Pap answer. Our findings point out the significance of utilizing an applicable fixative for preserving HLA-G cell floor antigen for research utilizing the MEM-G/9 antibody.

Produkcja w Escherichia coli rekombinowanych fragmentów białka wypustek COVID-19 połączonych z CRM197 

Throughout 2020, the COVID-19 pandemic affected virtually 108 people. Fairly a variety of vaccines towards COVID-19 had been subsequently developed, and some not too long ago obtained authorization for emergency use. General, these vaccines goal particular viral proteins by antibodies whose synthesis is immediately elicited or not directly triggered by nucleic acids coding for the specified targets. Amongst these targets, the receptor binding area (RBD) of COVID-19 spike protein (SP) does often happen within the repertoire of candidate vaccines. Nevertheless, the immunogenicity of RBD per se is restricted by its low molecular mass, and by a structural rearrangement of full-length SP accompanied by the detachment of RBD.

Right here we present that the RBD of COVID-19 SP might be conveniently produced in Escherichia coli when fused to a fraction of CRM197, a variant of diphtheria toxin at present used for a variety of conjugated vaccines. Particularly, we present that the CRM197-RBD chimera solubilized from inclusion our bodies might be refolded and purified to a state that includes the 5 native disulphide bonds of the parental proteins, the competence in binding angiotensin-converting enzyme 2, and a passable stability at room temperature. Accordingly, our observations present obligatory data for the event of a candidate vaccine directed towards COVID-19.

Szlak GluN2B-BDNF w jądrze kontaktującym się z płynem mózgowo-rdzeniowym pośredniczy w bólu neuropatycznym wywołanym urazem nerwu u szczurów 

The current examine was aimed to analyze the function of GluN2B-BDNF pathway within the cerebrospinal fluid-contacting nucleus (CSF-CN) in neuropathic ache. Intra-lateral ventricle injection of cholera toxin subunit B conjugated with horseradish peroxidase (CBHRP) was used to label the CSF-CN. Double-labeled immunofluorescent staining and Western blot had been used to watch the expression of GluN2B and BDNF within the CSF-CN. Persistent constriction damage of sciatic nerve (CCI) rat mannequin was used to duplicate the neuropathic ache.

Ache conduct was scored to find out the analgesic results of GluN2B antagonist Ro 25-6981 and BDNF neutralizing antibody on CCI rats. GluN2B and BDNF had been expressed within the CSF-CN and their expression was up-regulated in CCI rats. Intra-lateral ventricle injection of GluN2B antagonist Ro 25-6981 or BDNF neutralizing antibody notably alleviated thermal hyperalgesia and mechanical allodynia in CCI rats. Furthermore, the elevated expression of BDNF protein in CCI rats was reversed by intra-lateral ventricle injection of Ro 25-6981. These outcomes recommend that GluN2B and BDNF are expressed within the CSF-CN and alteration of GluN2B-BDNF pathway within the CSF-CN is concerned within the modulation of the peripheral neuropathic ache.

AF594 Phalloidin [equivalent to Alexa Fluor® 594 phalloidin]

23158 300 Tests
EUR 367.2

EGFR antibody (Alexa Fluor 488)

61R-E109BAF 125 ug
EUR 847.2
Description: Mouse monoclonal EGFR antibody (Alexa Fluor 488)

Endoglin/CD105 Alexa Fluor

FC15024 100 Tests
EUR 537.6

Anti-CD40 antibody (Alexa-fluor 488)

STJ170000 100 µg
EUR 471.6
Description: CD40 (48 to 50 kDa) is a transmembrane glycoprotein mainly expressed on the surface of B cells and also expressed on monocytes, dendritic cells, and thymic epithelium. CD40 is a member of the tumor necrosis factor (TNF) receptor superfamily, which includes the low affinity nerve growth factor (NGF) receptor and CD95/Fas. CD40 is the receptor for CD40 ligand. CD40L (CD40L, CD154, gp39, and TRAM) belongs to the TNF gene family and is expressed more widely than CD40, predominantly on activated CD4+ T cells. Following interaction with CD40 ligand, CD40 mediates a number of major immunoregulatory functions, central to the control of thymus dependent humoral immunity and may be critical in the development of cell mediated immune responses. Other biological actions include B cell homotypic adhesion, proliferation, immunoglobulin isotype switch, and secretion. Activation of CD40 has also been shown to inhibit the growth of certain B cell lymphomas and to induce the death of transformed cells of mesenchymal or epithelial origin

Anti-LAMP3 antibody (Alexa-fluor 488)

STJ170004 100 µg
EUR 471.6
Description: The dendritic cell lysosomal-associated membrane protein (DC-LAMP)/CD208 is a type I integral transmembrane glycoprotein mostly homologous to CD68, of about 45 kDa in mouse and 90 kDa in human (glycosylation), with a bipartite C-terminal structure divided by a serine/proline rich region, a transmembrane domain and a conserved tyrosine-based lysosomal targeting motif in its cytoplasmic tail. Initially cloned as a specific marker of human mature dendritic cells (DCs), DC-LAMP has been subsequently shown to be expressed in alveolar type II pneumocytes. In both cell types, the molecule is found in the limiting membrane of intracellular multi-lamellar bodies, known as MIIC (MHC class II compartments) in human mature DCs and as lung surfactant-containing lamellar bodies in type II pneumocytes. In the latter cell type, DC-LAMP expression is also detected at the cell surface.

Anti-LAMP3 antibody (Alexa-fluor 546)

STJ170005 100 µg
EUR 471.6
Description: The dendritic cell lysosomal-associated membrane protein (DC-LAMP)/CD208 is a type I integral transmembrane glycoprotein mostly homologous to CD68, of about 45 kDa in mouse and 90 kDa in human (glycosylation), with a bipartite C-terminal structure divided by a serine/proline rich region, a transmembrane domain and a conserved tyrosine-based lysosomal targeting motif in its cytoplasmic tail. Initially cloned as a specific marker of human mature dendritic cells (DCs), DC-LAMP has been subsequently shown to be expressed in alveolar type II pneumocytes. In both cell types, the molecule is found in the limiting membrane of intracellular multi-lamellar bodies, known as MIIC (MHC class II compartments) in human mature DCs and as lung surfactant-containing lamellar bodies in type II pneumocytes. In the latter cell type, DC-LAMP expression is also detected at the cell surface.

Anti-LAMP3 antibody (Alexa-fluor 647)

STJ170006 100 µg
EUR 471.6
Description: The dendritic cell lysosomal-associated membrane protein (DC-LAMP)/CD208 is a type I integral transmembrane glycoprotein mostly homologous to CD68, of about 45 kDa in mouse and 90 kDa in human (glycosylation), with a bipartite C-terminal structure divided by a serine/proline rich region, a transmembrane domain and a conserved tyrosine-based lysosomal targeting motif in its cytoplasmic tail. Initially cloned as a specific marker of human mature dendritic cells (DCs), DC-LAMP has been subsequently shown to be expressed in alveolar type II pneumocytes. In both cell types, the molecule is found in the limiting membrane of intracellular multi-lamellar bodies, known as MIIC (MHC class II compartments) in human mature DCs and as lung surfactant-containing lamellar bodies in type II pneumocytes. In the latter cell type, DC-LAMP expression is also detected at the cell surface.

Anti-IL3RA antibody (Alexa-fluor 488)

STJ170009 100 µg
EUR 471.6
Description: IL3 exerts its biologic activity through its interaction with a cell surface receptor that consists of two subunits. The a subunit (CD123) specifically binds IL3, whereas the ß subunit is required for signaling and is common to the GMCSFR and IL5-R. 107D2.08 and 106C2.02 mAbs were obtained after mouse immunization with sorted human tonsillar PDC. Both clones strongly stain PDCs and basophils, weakly stain monocytes, CD34+ derived DCs and CD11c+ DC, while no staining is observed on T, B, NK cells as well as on mono-derived DCs. Staining with 107D2.08 and 106C2.02 mAbs are maintained on sorted PDC cultured in the presence of IL3 and CD40L, but lost when IL3 alone is added to the culture. The recognition of the IL3Ra chain by 107D2.08 and 106C2.02 was confirmed by transfection studies. 107D2.08 appeared to be the most appropriate clone for in situ studies. 107D2.08 allowed the first observation of IL3Ra+ cells in breast tumor microenvironment

Anti-IL3RA antibody (Alexa-fluor 546)

STJ170010 100 µg
EUR 471.6
Description: IL3 exerts its biologic activity through its interaction with a cell surface receptor that consists of two subunits. The a subunit (CD123) specifically binds IL3, whereas the ß subunit is required for signaling and is common to the GMCSFR and IL5-R. 107D2.08 and 106C2.02 mAbs were obtained after mouse immunization with sorted human tonsillar PDC. Both clones strongly stain PDCs and basophils, weakly stain monocytes, CD34+ derived DCs and CD11c+ DC, while no staining is observed on T, B, NK cells as well as on mono-derived DCs. Staining with 107D2.08 and 106C2.02 mAbs are maintained on sorted PDC cultured in the presence of IL3 and CD40L, but lost when IL3 alone is added to the culture. The recognition of the IL3Ra chain by 107D2.08 and 106C2.02 was confirmed by transfection studies. 107D2.08 appeared to be the most appropriate clone for in situ studies. 107D2.08 allowed the first observation of IL3Ra+ cells in breast tumor microenvironment

Anti-IL3RA antibody (Alexa-fluor 647)

STJ170011 100 µg
EUR 471.6
Description: IL3 exerts its biologic activity through its interaction with a cell surface receptor that consists of two subunits. The a subunit (CD123) specifically binds IL3, whereas the ß subunit is required for signaling and is common to the GMCSFR and IL5-R. 107D2.08 and 106C2.02 mAbs were obtained after mouse immunization with sorted human tonsillar PDC. Both clones strongly stain PDCs and basophils, weakly stain monocytes, CD34+ derived DCs and CD11c+ DC, while no staining is observed on T, B, NK cells as well as on mono-derived DCs. Staining with 107D2.08 and 106C2.02 mAbs are maintained on sorted PDC cultured in the presence of IL3 and CD40L, but lost when IL3 alone is added to the culture. The recognition of the IL3Ra chain by 107D2.08 and 106C2.02 was confirmed by transfection studies. 107D2.08 appeared to be the most appropriate clone for in situ studies. 107D2.08 allowed the first observation of IL3Ra+ cells in breast tumor microenvironment

Anti-CD207 antibody (Alexa-fluor 488)

STJ170014 100 µg
EUR 471.6
Description: Langerin/CD207 is a transmembrane C-type lectin receptor (CLR) of epidermal and mucosal Langerhans cells (LCs) that induces Birbeck's granule formation. Langerin features a single carbohydrate recognition domain (CRD) with mannose-type specificity in its extracellular portion. Langerin is unique among the CLRs in that it contains an intracellular domain with a proline-rich motif. Langerin expression has not been reported outside the DC system. (Valladeau J et al, 1999, Eur.J.Immunol., 29:2695-2704; Valladeau J et al, 2000 Immunity, 12 : 71-81; Kashihara M et al, 1986, J.Invest.Derm., 87 :602-607 Ito T et al, 1999, J.Immunol., 163 :1409-1419 ;Saeland S & Valladeau J, CD207 (Langerin) Workshop reports 2002, Leukocyte-Typing VII, White Cell Diff Antigens, D. Mason et al, Eds, Oxford University Press:306-307)

Anti-CD207 antibody (Alexa-fluor 546)

STJ170015 100 µg
EUR 471.6
Description: Langerin/CD207 is a transmembrane C-type lectin receptor (CLR) of epidermal and mucosal Langerhans cells (LCs) that induces Birbeck's granule formation. Langerin features a single carbohydrate recognition domain (CRD) with mannose-type specificity in its extracellular portion. Langerin is unique among the CLRs in that it contains an intracellular domain with a proline-rich motif. Langerin expression has not been reported outside the DC system. (Valladeau J et al, 1999, Eur.J.Immunol., 29:2695-2704; Valladeau J et al, 2000 Immunity, 12 : 71-81; Kashihara M et al, 1986, J.Invest.Derm., 87 :602-607 Ito T et al, 1999, J.Immunol., 163 :1409-1419 ;Saeland S & Valladeau J, CD207 (Langerin) Workshop reports 2002, Leukocyte-Typing VII, White Cell Diff Antigens, D. Mason et al, Eds, Oxford University Press:306-307)

Anti-CD207 antibody (Alexa-fluor 647)

STJ170016 100 µg
EUR 471.6
Description: Langerin/CD207 is a transmembrane C-type lectin receptor (CLR) of epidermal and mucosal Langerhans cells (LCs) that induces Birbeck's granule formation. Langerin features a single carbohydrate recognition domain (CRD) with mannose-type specificity in its extracellular portion. Langerin is unique among the CLRs in that it contains an intracellular domain with a proline-rich motif. Langerin expression has not been reported outside the DC system. (Valladeau J et al, 1999, Eur.J.Immunol., 29:2695-2704; Valladeau J et al, 2000 Immunity, 12 : 71-81; Kashihara M et al, 1986, J.Invest.Derm., 87 :602-607 Ito T et al, 1999, J.Immunol., 163 :1409-1419 ;Saeland S & Valladeau J, CD207 (Langerin) Workshop reports 2002, Leukocyte-Typing VII, White Cell Diff Antigens, D. Mason et al, Eds, Oxford University Press:306-307)

Anti-IL7R antibody (Alexa-fluor 488)

STJ170020 100 µg
EUR 471.6
Description: The IL7-R consists of 2 chains, IL-7R known as CD127 and common cytokine receptor chain known as CD132. A 75 to 80kDa human IL-7 receptor has been cloned that belongs to hematopoietic cytokinereceptor super family. R34-34, raised against human leukemic pre-B cells, recognized a molecule expressed on normal B cell precursors but not on mature B cells. This antibody specifically reverted IL-7 mediated growth inhibition of leukemic BCP (normal B cells precursors) and mature T cells. IL-7R expression is dramatically influenced by cytokines and antigens. This IL-7R displays both high and low affinity for its ligand (IL-7). Inhibitory and proliferative effects of IL-7 can be mediated through the same receptor on various lineages. CD4+ memory T cells express high level of IL-7R Subsets that express it generally require it, including progenitors of T and B cells, naïve and memory T cells. (Pandrau-Garcia D et al, 1994, Blood, 83, 3613-9 Mazzucchelli R et al, Nat. Review Immunol., 2007,7, 144-54)

Anti-IL7R antibody (Alexa-fluor 546)

STJ170021 100 µg
EUR 471.6
Description: The IL7-R consists of 2 chains, IL-7R known as CD127 and common cytokine receptor chain known as CD132. A 75 to 80kDa human IL-7 receptor has been cloned that belongs to hematopoietic cytokinereceptor super family. R34-34, raised against human leukemic pre-B cells, recognized a molecule expressed on normal B cell precursors but not on mature B cells. This antibody specifically reverted IL-7 mediated growth inhibition of leukemic BCP (normal B cells precursors) and mature T cells. IL-7R expression is dramatically influenced by cytokines and antigens. This IL-7R displays both high and low affinity for its ligand (IL-7). Inhibitory and proliferative effects of IL-7 can be mediated through the same receptor on various lineages. CD4+ memory T cells express high level of IL-7R Subsets that express it generally require it, including progenitors of T and B cells, naïve and memory T cells. (Pandrau-Garcia D et al, 1994, Blood, 83, 3613-9 Mazzucchelli R et al, Nat. Review Immunol., 2007,7, 144-54)

Anti-IL7R antibody (Alexa-fluor 647)

STJ170022 100 µg
EUR 471.6
Description: The IL7-R consists of 2 chains, IL-7R known as CD127 and common cytokine receptor chain known as CD132. A 75 to 80kDa human IL-7 receptor has been cloned that belongs to hematopoietic cytokinereceptor super family. R34-34, raised against human leukemic pre-B cells, recognized a molecule expressed on normal B cell precursors but not on mature B cells. This antibody specifically reverted IL-7 mediated growth inhibition of leukemic BCP (normal B cells precursors) and mature T cells. IL-7R expression is dramatically influenced by cytokines and antigens. This IL-7R displays both high and low affinity for its ligand (IL-7). Inhibitory and proliferative effects of IL-7 can be mediated through the same receptor on various lineages. CD4+ memory T cells express high level of IL-7R Subsets that express it generally require it, including progenitors of T and B cells, naïve and memory T cells. (Pandrau-Garcia D et al, 1994, Blood, 83, 3613-9 Mazzucchelli R et al, Nat. Review Immunol., 2007,7, 144-54)

Donkey anti Goat IgG (H + L) (Fab 2) (Alexa Fluor 594)

43R-ID012AF 300 ug
EUR 492
Description: Donkey anti Goat IgG (H + L) secondary antibody (Fab'2) (Alexa Fluor 594)

Donkey Anti-Goat IgG (H+L), Alexa Fluor® 594 Conjugated

Ab8011-001 1mg
EUR 400.8

SAM FCM (Alexa Fluor 647)

abx098902-100tests 100 tests
EUR 1479.6

SAM FCM (Alexa Fluor 488)

abx098904-60tests 60 tests
EUR 1629.6

Anti-RPSA Alexa Fluor® 488

A4-829-C100 0.1 mg
EUR 372

Anti-Hu CD34 Alexa Fluor488

A4-297-T025 25 tests
EUR 184.8

Anti-Hu CD34 Alexa Fluor488

A4-297-T100 100 tests
EUR 322.8

Anti-Hu CD34 Alexa Fluor700

A7-297-T025 25 tests
EUR 184.8

Anti-Hu CD34 Alexa Fluor700

A7-297-T100 100 tests
EUR 322.8

Goat anti Mouse IgG1 (Alexa Fluor 488)

43R-1649 500 ug
EUR 684
Description: Goat anti Mouse IgG1 secondary antibody (Alexa Fluor 488)

Anti-Hu CD16 Alexa Fluor® 488

A4-646-T100 100 tests
EUR 322.8

Rabbit Anti-Rat IgG (H+L)-Alexa 594 Fluor conjugate (adsorbed with human IgG)

50337 0.5 ml
EUR 270

Alpha Fluor™ 594 NHS Ester

1830 1 mg
EUR 262.8

Alpha Fluor™ 594 C5 Maleimide

1891 1 mg
EUR 262.8

Streptavidin-Alexa594 (Alexas fluor 594) conjugate

SV-A594-100 100 tests
EUR 270

Alpha Fluor™ 488 acid [equivalent to Alexa Fluor™ 488 acid]

1790 5 mg
EUR 367.2

Alpha Fluor™ 532 acid [equivalent to Alexa Fluor™ 532 acid]

1795 10 mg
EUR 471.6

Donkey anti Goat IgG (H + L) (Alexa Fluor 647)

43R-ID028AF 500 ug
EUR 516
Description: Donkey anti Goat IgG (H + L) secondary antibody (Alexa Fluor 647)

Donkey anti Chicken IgY (H + L) (Alexa Fluor 647)

43R-ID060AF 300 ug
EUR 510
Description: Donkey anti Chicken IgY (H + L) (Fab'2) (Alexa Fluor 647)

AF350-streptavidin conjugate [Streptavidin, Alexa Fluor™ 350 Conjugate]

16890 1 mg
EUR 211.2

AF488-streptavidin conjugate [Streptavidin, Alexa Fluor™ 488 Conjugate]

16891 1 mg
EUR 211.2

AF350 Phalloidin [equivalent to Alexa Fluor® 350 phalloidin]

23150 300 Tests
EUR 367.2

AF488 Phalloidin [equivalent to Alexa Fluor® 488 phalloidin]

23153 300 Tests
EUR 367.2

Anti-Hu CD72 Alexa Fluor® 488

A4-310-T100 100 tests
EUR 322.8

Anti-Bov CD9 Alexa Fluor® 488

A4-354-C100 0.1 mg
EUR 322.8

Anti-Hu CD30 Alexa Fluor® 700

A7-455-T100 100 tests
EUR 322.8

Anti-Hu CD94 Alexa Fluor® 700

A7-727-T100 100 tests
EUR 322.8

Anti-Hu CD56 Alexa Fluor® 700

A7-789-T100 100 tests
EUR 322.8

Anti-LAMP3 (human) Monoclonal Antibody (104G4) (Alexa Fluor® 488)

M09406 100ug
EUR 678
Description: Mouse Monoclonal LAMP3 (human) Antibody (104G4) (Alexa Fluor® 488). Validated in IHC and tested in Human.

Anti-Hu CD3 zeta (pY153) Alexa Fluor® 488

A4-686-C100 0.1 mg
EUR 322.8

Anti-Hu CD3 zeta (pY72) Alexa Fluor® 488

A4-712-C100 0.1 mg
EUR 322.8

Anti-Hu CD3 zeta (pY142) Alexa Fluor® 488

A4-730-C100 0.1 mg
EUR 322.8

Anti-Hu CD3 zeta (pY111) Alexa Fluor® 488

A4-737-C100 0.1 mg
EUR 322.8

Donkey Anti-Rabbit IgG (H+L), Alexa Fluor® 488 Conjugated

Ab8032-001 0.5mg
EUR 522

Anti-Hu CD3 zeta (pY153) Alexa Fluor® 647

A6-686-C100 0.1 mg
EUR 322.8

Anti-Hu CD3 zeta (pY72) Alexa Fluor® 647

A6-712-C100 0.1 mg
EUR 322.8

Anti-Hu CD3 zeta (pY142) Alexa Fluor® 647

A6-730-C100 0.1 mg
EUR 322.8

Anti-Hu CD3 zeta (pY111) Alexa Fluor® 647

A6-737-C100 0.1 mg
EUR 322.8

Anti-Langerin (human) Monoclonal Antibody (DCGM4/122D5) (Alexa Fluor® 488)

M02316 100ug
EUR 696
Description: Mouse Monoclonal Langerin (human) Antibody (DCGM4/122D5) (Alexa Fluor® 488). Validated in IHC and tested in Human.

Human Cluster Of Differentiation 34 (CD34) ELISA Kit

DLR-CD34-Hu-48T 48T
EUR 597.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Cluster Of Differentiation 34 (CD34) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Cluster Of Differentiation 34 (CD34) ELISA Kit

DLR-CD34-Hu-96T 96T
EUR 776.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Cluster Of Differentiation 34 (CD34) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Cluster Of Differentiation 34 (CD34) ELISA Kit

DLR-CD34-Mu-48T 48T
EUR 609.6
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Cluster Of Differentiation 34 (CD34) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Cluster Of Differentiation 34 (CD34) ELISA Kit

DLR-CD34-Mu-96T 96T
EUR 793.2
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Cluster Of Differentiation 34 (CD34) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Cluster Of Differentiation 34 (CD34) ELISA Kit

RD-CD34-Hu-48Tests 48 Tests
EUR 600

Human Cluster Of Differentiation 34 (CD34) ELISA Kit

RD-CD34-Hu-96Tests 96 Tests
EUR 830.4

Mouse Cluster Of Differentiation 34 (CD34) ELISA Kit

RD-CD34-Mu-48Tests 48 Tests
EUR 613.2

Mouse Cluster Of Differentiation 34 (CD34) ELISA Kit

RD-CD34-Mu-96Tests 96 Tests
EUR 850.8

Human Cluster Of Differentiation 34 (CD34) ELISA Kit

RDR-CD34-Hu-48Tests 48 Tests
EUR 626.4

Human Cluster Of Differentiation 34 (CD34) ELISA Kit

RDR-CD34-Hu-96Tests 96 Tests
EUR 868.8

Mouse Cluster Of Differentiation 34 (CD34) ELISA Kit

RDR-CD34-Mu-48Tests 48 Tests
EUR 640.8

Mouse Cluster Of Differentiation 34 (CD34) ELISA Kit

RDR-CD34-Mu-96Tests 96 Tests
EUR 890.4

CD34 antigen (CD34) polyclonal antibody

ABP-PAB-00010 100 ug Ask for price

CD34 antibody

70R-10219 50 ug
EUR 560.4
Description: Affinity purified rabbit polyclonal CD34 antibody

CD34 antibody

70R-10220 50 ug
EUR 560.4
Description: Affinity purified rabbit polyclonal CD34 antibody

CD34 Antibody

43792-100ul 100ul
EUR 302.4

CD34 antibody

70R-13876 100 ug
EUR 366
Description: Affinity purified Rabbit polyclonal CD34 antibody

CD34 antibody

38153-100ul 100ul
EUR 302.4

CD34 Antibody

48740-100ul 100ul
EUR 399.6

CD34 Antibody

48740-50ul 50ul
EUR 286.8

CD34 Antibody

35493-100ul 100ul
EUR 468

CD34 Antibody

35494-100ul 100ul
EUR 468

CD34 antibody

20R-2517 50 ug
EUR 337.2
Description: Rabbit polyclonal CD34 antibody

CD34 antibody

10R-6385 100 ug
EUR 243.6
Description: Mouse monoclonal CD34 antibody

CD34 antibody

10R-7653 50 ug
EUR 548.4
Description: Mouse monoclonal CD34 antibody

CD34 antibody

10R-1923 100 ul
EUR 522
Description: Mouse monoclonal CD34 antibody

CD34 antibody

10R-2342 1 mL
EUR 706.8
Description: Mouse monoclonal CD34 antibody

CD34 Antibody

21469-100ul 100ul
EUR 302.4

CD34 Antibody

21469-50ul 50ul
EUR 224.4

CD34 Antibody

ABF4036 100 ug
EUR 525.6

CD34 Antibody

ABF5149 100 ug
EUR 525.6

CD34 Antibody

ABD6139 100 ug
EUR 525.6

CD34 Antibody

20-abx242939
  • EUR 560.40
  • EUR 393.60
  • 100 ul
  • 50 ul

CD34 Antibody

BF0423 200ul
EUR 540

CD34 Antibody

1-CSB-PA001451
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against CD34. Recognizes CD34 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/10000

CD34 Antibody

DF6139 200ul
EUR 420

CD34 Antibody

DF16119 100ul
EUR 420

CD34 Antibody

AF4036 200ul
EUR 540

CD34 Antibody

AF5149 200ul
EUR 420

CD34 Antibody

1-CSB-PA10509A0Rb
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against CD34. Recognizes CD34 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF; Recommended dilution: WB:1:2000-1:5000, IHC:1:20-1:200, IF:1:50-1:200

CD34 Antibody

CSB-PA269036-
EUR 402
Description: A polyclonal antibody against CD34. Recognizes CD34 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

CD34 Antibody

CSB-PA269036-100ul 100ul
EUR 379.2
Description: A polyclonal antibody against CD34. Recognizes CD34 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

CD34 Antibody

CSB-PA004926KA01HU-
EUR 402
Description: A polyclonal antibody against CD34. Recognizes CD34 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:2000, IHC:1:50-1:200

CD34 Antibody

CSB-PA004926KA01HU-100ul 100ul
EUR 466.8
Description: A polyclonal antibody against CD34. Recognizes CD34 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:2000, IHC:1:50-1:200

Rabbit Anti-Rat IgG (H+L)-Alexa 488 Fluor conjugate (adsorbed with human IgG)

50336 0.5 ml
EUR 270

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

abx159385-100ul 100 ul
EUR 427.2

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

20-abx137239
  • EUR 844.80
  • EUR 393.60
  • EUR 276.00
  • 100 ug
  • 20 ug
  • 5 ug

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

abx139245-01mg 0.1 mg
EUR 427.2

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

abx139246-01mg 0.1 mg
EUR 427.2

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

abx140187-01mg 0.1 mg
EUR 427.2

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

20-abx134248
  • EUR 427.20
  • EUR 678.00
  • EUR 360.00
  • 100 ul
  • 200 ul
  • 50 ul

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

abx146497-100ug 100 ug
EUR 469.2

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

20-abx006947
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

20-abx000850
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

20-abx121327
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

20-abx125016
  • EUR 493.20
  • EUR 710.40
  • 100 ul
  • 200 ul

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

20-abx125311
  • EUR 710.40
  • EUR 1028.40
  • EUR 493.20
  • 100 ul
  • 200 ul
  • 50 ul

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

abx117011-100ug 100 ug
EUR 560.4

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

abx010523-100ul 100 ul
EUR 493.2

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

abx019048-100ug 100 ug
EUR 410.4

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

abx025833-400ul 400 ul
EUR 627.6

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

abx025833-80l 80 µl
EUR 343.2

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

abx025185-400ul 400 ul
EUR 627.6

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

abx025185-80l 80 µl
EUR 343.2

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

20-abx200774
  • EUR 309.60
  • EUR 678.00
  • 100 ug
  • 500 ug

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

20-abx318004
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

abx413200-01mg 0.1 mg
EUR 526.8

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

abx413400-025mg 0.25 mg
EUR 678

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

abx413401-05mg 0.5 mg
EUR 994.8

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

abx413405-01mg 0.1 mg
EUR 526.8

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

abx413408-25ug 25 ug
EUR 326.4

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

abx414153-01mg 0.1 mg
EUR 543.6

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

abx415036-02mg 0.2 mg
EUR 678

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

abx415037-25ug 25 ug
EUR 326.4

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

abx415252-01mg 0.1 mg
EUR 543.6

Hematopoietic Progenitor Cell Antigen CD34 (CD34) Antibody

abx231469-100ug 100 ug
EUR 577.2

CD34 antibody (FITC)

61R-1073 100 tests
EUR 418.8
Description: Mouse monoclonal CD34 antibody (FITC)

CD34 antibody (PE)

61R-1238 100 tests
EUR 548.4
Description: Mouse monoclonal CD34 antibody (PE)

CD34 antibody (allophycocyanin)

61R-1722 100 tests
EUR 548.4
Description: Mouse monoclonal CD34 antibody (allophycocyanin)

CD34 Antibody (Center)

6797-100
EUR 379.2

CD34 Polyclonal Antibody

40701-100ul 100ul
EUR 302.4

CD34 Polyclonal Antibody

40701-50ul 50ul
EUR 224.4

CD34 Polyclonal Antibody

ABP50908-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of CD34 from Human, Mouse. This CD34 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human CD34

CD34 Polyclonal Antibody

ABP50908-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of CD34 from Human, Mouse. This CD34 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human CD34

CD34 Polyclonal Antibody

ABP50908-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of CD34 from Human, Mouse. This CD34 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human CD34

CD34-T Antibody

abx431151-200ul 200 ul
EUR 460.8

CD34 Conjugated Antibody

C48740 100ul
EUR 476.4

CD34 Conjugated Antibody

C21469 100ul
EUR 476.4

CD34 Polyclonal Antibody

ES1907-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against CD34 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

CD34 Polyclonal Antibody

ES1907-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against CD34 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

Anti-CD34 antibody

PAab01469 100 ug
EUR 426

anti- CD34 antibody

FNab01469 100µg
EUR 606.3
Description: Antibody raised against CD34

Anti-CD34 Antibody

PA1334 100ug/vial
EUR 400.8

Anti-CD34 Antibody

PB9053 100ug/vial
EUR 400.8

Anti-CD34 antibody

STJ115864 100 µl
EUR 332.4
Description: The protein encoded by this gene may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells. This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C. Two transcript variants encoding different isoforms have been found for this gene.

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