• 30 kwietnia, 2021
bodiesrevealed

Strukturalny wpływ glikodendrymerów rekrutujących

Strukturalny wpływ glikodendrymerów rekrutujących przeciwciała (ARG) na cytotoksyczność przeciwnowotworową 

  • The recruitment of endogenous antibodies towards most cancers cells has develop into a dependable antitumoral immunotherapeutic various over the past decade. The covalent attachment of antibody and tumor binding modules (ABM and TBM) inside a single, well-defined artificial molecule was certainly demonstrated to advertise the formation of an interacting ternary advanced between each the antibodies and the focused cell, which often ends in the simultaneous immune-mediated mobile destruction.
  • In a preliminary examine, now we have described the primary Antibody Recruiting Glycodendrimers (ARGs), combining cRGD as ligands for the αVβ3-expressing melanoma cell line M21 and Rha as ligand for pure IgM, and demonstrated that multivalency is an important requirement to kind this advanced. Within the current examine, we synthesized a brand new sequence of ARGs composed of ABMs, i.e. self-condensed rhamnosylated cyclopeptide and polylysine dendrimer, which have been conjugated to the TBM with or with out spacer.
  • Circulate cytometry and confocal microscopy experiments with human serum and completely different cell traces revealed that the ABM geometry considerably influences the ternary advanced formation in M21, whereas no important binding happens in BT 549 having low integrin expression. As well as, we exhibit with a mobile viability assay that ARGs induce excessive degree of cytotoxicity towards M21 which can also be in shut correlation with the ABM construction.
  • Particularly, now we have proven that ARG combining cyclopeptide core and branches, with or with out spacer, induce 40-57% of selective cytotoxicity towards M21 cells within the presence of human serum because the distinctive supply of immunity effectors. Lastly, we additionally spotlight that the spacer between ABM and TBM permits a rise of the immune-mediate cytotoxicity even with ABM of decrease valency.
bodiesrevealed
bodiesrevealed

Mouse Anti-Human IgA - Alexa Fluor 555

E38A3434 100μL
EUR 125

Mouse Anti-Human IgM - Alexa Fluor 555

E38A3438 100μL
EUR 125

Mouse Anti-Human IgM - Alexa Fluor 555

YLF0309-100ul 100 ul
EUR 130
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgM - Alexa Fluor 555

YLF0309-1ml 1 ml
EUR 480
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgM - Alexa Fluor 555

YLF0309-500ul 500 ul
EUR 290
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgA - Alexa Fluor 555

YLF0536-100ul 100 ul
EUR 130
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgA - Alexa Fluor 555

YLF0536-1ml 1 ml
EUR 300
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgA - Alexa Fluor 555

YLF0536-500ul 500 ul
EUR 210
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Human IgM - Alexa Fluor 555

DL87293A-100ul 100 ul
EUR 190
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Human IgM - Alexa Fluor 555

DL87293A-500ul 500 ul
EUR 280
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Human IgM - Alexa Fluor 555

E38A3425 100μL
EUR 125

Rabbit Anti-Human IgM - Alexa Fluor 555

YLF0533-100ul 100 ul
EUR 130
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Human IgM - Alexa Fluor 555

YLF0533-1ml 1 ml
EUR 300
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Human IgM - Alexa Fluor 555

YLF0533-500ul 500 ul
EUR 210
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Bovine IgG (H&L) - Alexa Fluor 555

DL87280A-100ul 100 ul
EUR 155
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Bovine IgG (H&L) - Alexa Fluor 555

DL87280A-500ul 500 ul
EUR 350
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Bovine IgG (H&L) - Alexa Fluor 555

E38A3412 100μL
EUR 125

Rabbit Anti-Bovine IgG (H&L) - Alexa Fluor 555

YLF0292-100ul 100 ul
EUR 130
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Bovine IgG (H&L) - Alexa Fluor 555

YLF0292-1ml 1 ml
EUR 480
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Bovine IgG (H&L) - Alexa Fluor 555

YLF0292-500ul 500 ul
EUR 290
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Goat Anti-Human IgG Fc - Alexa Fluor 555

DL87272A-100ul 100 ul
EUR 155
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Goat Anti-Human IgG Fc - Alexa Fluor 555

DL87272A-500ul 500 ul
EUR 350
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Goat Anti-Human IgG Fc - Alexa Fluor 555

E38A3404 100μL
EUR 125

Goat Anti-Human IgG Fc - Alexa Fluor 555

YLF0287-100ul 100 ul
EUR 130
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Goat Anti-Human IgG Fc - Alexa Fluor 555

YLF0287-1ml 1 ml
EUR 480
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Goat Anti-Human IgG Fc - Alexa Fluor 555

YLF0287-500ul 500 ul
EUR 290
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

EGFR antibody (Alexa Fluor 488)

61R-E109BAF 125 ug
EUR 714
Description: Mouse monoclonal EGFR antibody (Alexa Fluor 488)

Goat Anti-Human IgG Fab - Alexa Fluor 555

DL87271A-100ul 100 ul
EUR 190
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Goat Anti-Human IgG Fab - Alexa Fluor 555

DL87271A-500ul 500 ul
EUR 280
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgG Fc - Alexa Fluor 555

DL87303A-100ul 100 ul
EUR 190
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgG Fc - Alexa Fluor 555

DL87303A-500ul 500 ul
EUR 280
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Goat Anti-Human IgG Fab - Alexa Fluor 555

E38A3403 100μL
EUR 125

Mouse Anti-Human IgG Fc - Alexa Fluor 555

E38A3436 100μL
EUR 125

Goat Anti-Human IgG Fab - Alexa Fluor 555

YLF0530-100ul 100 ul
EUR 130
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Goat Anti-Human IgG Fab - Alexa Fluor 555

YLF0530-1ml 1 ml
EUR 300
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Goat Anti-Human IgG Fab - Alexa Fluor 555

YLF0530-500ul 500 ul
EUR 210
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgG Fc - Alexa Fluor 555

YLF0538-100ul 100 ul
EUR 130
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgG Fc - Alexa Fluor 555

YLF0538-1ml 1 ml
EUR 300
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgG Fc - Alexa Fluor 555

YLF0538-500ul 500 ul
EUR 210
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Human IgG Fc - Alexa Fluor 555

DL87290A-100ul 100 ul
EUR 155
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Human IgG Fc - Alexa Fluor 555

DL87290A-500ul 500 ul
EUR 350
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgG Fab - Alexa Fluor 555

DL87302A-100ul 100 ul
EUR 190
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgG Fab - Alexa Fluor 555

DL87302A-500ul 500 ul
EUR 280
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Human IgG Fc - Alexa Fluor 555

E38A3422 100ug/100ul
EUR 125
Description: Available in various conjugation types.

Mouse Anti-Human IgG Fab - Alexa Fluor 555

E38A3435 100μL
EUR 125

Rabbit Anti-Human IgG Fc - Alexa Fluor 555

YLF0302-100ul 100 ul
EUR 130
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Human IgG Fc - Alexa Fluor 555

YLF0302-1ml 1 ml
EUR 480
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Human IgG Fc - Alexa Fluor 555

YLF0302-500ul 500 ul
EUR 290
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgG Fab - Alexa Fluor 555

YLF0537-100ul 100 ul
EUR 130
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgG Fab - Alexa Fluor 555

YLF0537-1ml 1 ml
EUR 300
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Human IgG Fab - Alexa Fluor 555

YLF0537-500ul 500 ul
EUR 210
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Goat Anti-Pig IgG (H&L) - Alexa Fluor 555

DL87278A-100ul 100 ul
EUR 155
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Goat Anti-Pig IgG (H&L) - Alexa Fluor 555

DL87278A-500ul 500 ul
EUR 350
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Goat Anti-Pig IgG (H&L) - Alexa Fluor 555

E38A3410 100μL
EUR 125

Goat Anti-Pig IgG (H&L) - Alexa Fluor 555

YLF0291-100ul 100 ul
EUR 130
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Goat Anti-Pig IgG (H&L) - Alexa Fluor 555

YLF0291-1ml 1 ml
EUR 480
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Goat Anti-Pig IgG (H&L) - Alexa Fluor 555

YLF0291-500ul 500 ul
EUR 290
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Pig IgG (H&L) - Alexa Fluor 555

DL87307A-100ul 100 ul
EUR 190
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Pig IgG (H&L) - Alexa Fluor 555

DL87307A-500ul 500 ul
EUR 280
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Pig IgG (H&L) - Alexa Fluor 555

E38A3441 100μL
EUR 125

Mouse Anti-Pig IgG (H&L) - Alexa Fluor 555

YLF0541-100ul 100 ul
EUR 130
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Pig IgG (H&L) - Alexa Fluor 555

YLF0541-1ml 1 ml
EUR 300
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Pig IgG (H&L) - Alexa Fluor 555

YLF0541-500ul 500 ul
EUR 210
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

HAPLN2 antibody

70R-9514 50 ug
EUR 467
Description: Affinity purified rabbit polyclonal HAPLN2 antibody

HAPLN2 Antibody

GWB-MU874A 50ug Ask for price

Goat Anti-Human IgG (H&L) - Alexa Fluor 555

DL87270A-100ul 100 ul
EUR 140
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Goat Anti-Human IgG (H&L) - Alexa Fluor 555

DL87270A-500ul 500 ul
EUR 330
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Goat Anti-Mouse IgG (H&L) - Alexa Fluor 555

DL87276A-100ul 100 ul
EUR 140
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Goat Anti-Mouse IgG (H&L) - Alexa Fluor 555

DL87276A-500ul 500 ul
EUR 330
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Cat IgG (H&L) - Alexa Fluor 555

DL87281A-100ul 100 ul
EUR 155
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Cat IgG (H&L) - Alexa Fluor 555

DL87281A-500ul 500 ul
EUR 350
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Dog IgG (H&L) - Alexa Fluor 555

DL87283A-100ul 100 ul
EUR 155
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Dog IgG (H&L) - Alexa Fluor 555

DL87283A-500ul 500 ul
EUR 350
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Pig IgG (H&L) - Alexa Fluor 555

DL87296A-100ul 100 ul
EUR 155
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Pig IgG (H&L) - Alexa Fluor 555

DL87296A-500ul 500 ul
EUR 350
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Rat IgG (H&L) - Alexa Fluor 555

DL87297A-100ul 100 ul
EUR 155
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Rat IgG (H&L) - Alexa Fluor 555

DL87297A-500ul 500 ul
EUR 350
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Duck IgY (H&L) - Alexa Fluor 555

DL87300A-100ul 100 ul
EUR 190
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Mouse Anti-Duck IgY (H&L) - Alexa Fluor 555

DL87300A-500ul 500 ul
EUR 280
Description: The antibody was isolated from ascitic by immunoaffinity chromatography using antigens coupled to agarose beads.

Goat Anti-Human IgG (H&L) - Alexa Fluor 555

E38A3402 100μL
EUR 125

Goat Anti-Mouse IgG (H&L) - Alexa Fluor 555

E38A3408 100μL
EUR 125

Rabbit Anti-Cat IgG (H&L) - Alexa Fluor 555

E38A3413 100μL
EUR 125

Rabbit Anti-Dog IgG (H&L) - Alexa Fluor 555

E38A3415 100μL
EUR 125

Rabbit Anti-Pig IgG (H&L) - Alexa Fluor 555

E38A3428 100μL
EUR 125

Rabbit Anti-Rat IgG (H&L) - Alexa Fluor 555

E38A3429 100μL
EUR 125

Mouse Anti-Duck IgY (H&L) - Alexa Fluor 555

E38A3433 100μL
EUR 125

Goat Anti-Human IgG (H&L) - Alexa Fluor 555

YLF0103-100ul 100 ul
EUR 100
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Goat Anti-Human IgG (H&L) - Alexa Fluor 555

YLF0103-1ml 1 ml
EUR 490
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Goat Anti-Human IgG (H&L) - Alexa Fluor 555

YLF0103-500ul 500 ul
EUR 300
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Goat Anti-Mouse IgG (H&L) - Alexa Fluor 555

YLF0104-100ul 100 ul
EUR 100
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Goat Anti-Mouse IgG (H&L) - Alexa Fluor 555

YLF0104-1ml 1 ml
EUR 490
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Goat Anti-Mouse IgG (H&L) - Alexa Fluor 555

YLF0104-500ul 500 ul
EUR 300
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Cat IgG (H&L) - Alexa Fluor 555

YLF0293-100ul 100 ul
EUR 130
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Cat IgG (H&L) - Alexa Fluor 555

YLF0293-1ml 1 ml
EUR 480
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Cat IgG (H&L) - Alexa Fluor 555

YLF0293-500ul 500 ul
EUR 290
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Dog IgG (H&L) - Alexa Fluor 555

YLF0295-100ul 100 ul
EUR 130
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Dog IgG (H&L) - Alexa Fluor 555

YLF0295-1ml 1 ml
EUR 480
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Dog IgG (H&L) - Alexa Fluor 555

YLF0295-500ul 500 ul
EUR 290
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Pig IgG (H&L) - Alexa Fluor 555

YLF0306-100ul 100 ul
EUR 130
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

Rabbit Anti-Pig IgG (H&L) - Alexa Fluor 555

YLF0306-1ml 1 ml
EUR 480
Description: The antibody was isolated from antisera by immunoaffinity chromatography using antigens coupled to agarose beads.

ICELISA na bazie przeciwciał monoklonalnych do badania przesiewowego diazynonu w próbkach warzyw 

Diazinon (DAZ) is an organophosphorus pesticide (OP), which is often used to stop and management dangerous pests that endanger agricultural merchandise. On this examine, we developed a novel heterology coating technique for the immunoassay of DAZ. The DAZ coating hapten might be immediately conjugated to the provider protein with out requiring a spacer arm. This proposed hapten coating technique is time-saving and considerably improves the sensitivity of the immunoassay because of the lack of a spacer arm. The as-synthesized coating antigen was used to display screen the monoclonal antibody (mAb).

Lastly, the developed oblique aggressive enzyme-linked immunoassay (icELISA) confirmed IC50 and restrict of detection (LOD) values of 0.58 ng mL-1 and eight pg mL-1, respectively. This methodology exhibited negligible cross-reactivity in direction of different analogues, and the recoveries of samples (cucumber, cabbage, and lettuce) ranged from 92.6% to 125.4%, with coefficients of variance (CV) beneath 12%. Good correlation between icELISA and high-performance liquid chromatography mass spectrometry (HPLC-MS/MS) was obtained. The proposed icELISA was a super instrument for monitoring DAZ residues in meals samples.

Odpowiedni środek utrwalający do barwienia MEM-G / 9 hodowanych ludzkich komórek nowotworowych trofoblastów JEG-Three HLA-G-dodatnich 

Human leukocyte antigen (HLA-G) participates in immunosuppression and is beneficial for prenatal diagnostics. Isolation of fetal cells optimistic for HLA-G by HLA-G antibody conjugated nanoparticles from the cervix of pregnant girls is the idea for non-invasive prenatal testing. Endocervical specimens are mounted in transport medium earlier than isolation utilizing antibody conjugated nanoparticles. Staining of HLA-G utilizing MEM-G/9 antibody, nonetheless, is restricted to unfixed cells. We investigated the impact of a number of fixatives on the interplay of HLA-G with MEM-G/9 within the HLA-G-positive cell line, JEG-3. We investigated absolute methanol, 1:1 acetate buffer:methanol, Pap answer and paraformaldehyde.

The results of those fixatives had been evaluated utilizing immunofluorescence. We discovered no MEM-G/9 floor staining of methanol mounted cells. Roughly 40% of JEG-Three cells mounted with paraformaldehyde didn’t stain. Almost all cells had been stained with MEM-G/9 following fixation with acetate buffer:methanol or Pap answer. Our findings point out the significance of utilizing an applicable fixative for preserving HLA-G cell floor antigen for research utilizing the MEM-G/9 antibody.

Produkcja w Escherichia coli rekombinowanych fragmentów białka wypustek COVID-19 połączonych z CRM197 

Throughout 2020, the COVID-19 pandemic affected virtually 108 people. Fairly a variety of vaccines towards COVID-19 had been subsequently developed, and some not too long ago obtained authorization for emergency use. General, these vaccines goal particular viral proteins by antibodies whose synthesis is immediately elicited or not directly triggered by nucleic acids coding for the specified targets. Amongst these targets, the receptor binding area (RBD) of COVID-19 spike protein (SP) does often happen within the repertoire of candidate vaccines. Nevertheless, the immunogenicity of RBD per se is restricted by its low molecular mass, and by a structural rearrangement of full-length SP accompanied by the detachment of RBD.

Right here we present that the RBD of COVID-19 SP might be conveniently produced in Escherichia coli when fused to a fraction of CRM197, a variant of diphtheria toxin at present used for a variety of conjugated vaccines. Particularly, we present that the CRM197-RBD chimera solubilized from inclusion our bodies might be refolded and purified to a state that includes the 5 native disulphide bonds of the parental proteins, the competence in binding angiotensin-converting enzyme 2, and a passable stability at room temperature. Accordingly, our observations present obligatory data for the event of a candidate vaccine directed towards COVID-19.

Szlak GluN2B-BDNF w jądrze kontaktującym się z płynem mózgowo-rdzeniowym pośredniczy w bólu neuropatycznym wywołanym urazem nerwu u szczurów 

The current examine was aimed to analyze the function of GluN2B-BDNF pathway within the cerebrospinal fluid-contacting nucleus (CSF-CN) in neuropathic ache. Intra-lateral ventricle injection of cholera toxin subunit B conjugated with horseradish peroxidase (CBHRP) was used to label the CSF-CN. Double-labeled immunofluorescent staining and Western blot had been used to watch the expression of GluN2B and BDNF within the CSF-CN. Persistent constriction damage of sciatic nerve (CCI) rat mannequin was used to duplicate the neuropathic ache.

Ache conduct was scored to find out the analgesic results of GluN2B antagonist Ro 25-6981 and BDNF neutralizing antibody on CCI rats. GluN2B and BDNF had been expressed within the CSF-CN and their expression was up-regulated in CCI rats. Intra-lateral ventricle injection of GluN2B antagonist Ro 25-6981 or BDNF neutralizing antibody notably alleviated thermal hyperalgesia and mechanical allodynia in CCI rats. Furthermore, the elevated expression of BDNF protein in CCI rats was reversed by intra-lateral ventricle injection of Ro 25-6981. These outcomes recommend that GluN2B and BDNF are expressed within the CSF-CN and alteration of GluN2B-BDNF pathway within the CSF-CN is concerned within the modulation of the peripheral neuropathic ache.

Alexa Fluor® 700 anti-human CD34

E16FHI034-025 25 tests
EUR 650
Description: Available in various conjugation types.

Alexa Fluor® 700 anti-human CD34

E16FHI034-100 100 tests
EUR 1538.33
Description: Available in various conjugation types.

Alexa Fluor® 647 anti-human CD34

E16FHK034-025 25 tests
EUR 455
Description: Available in various conjugation types.

Alexa Fluor® 647 anti-human CD34

E16FHK034-100 100 tests
EUR 975
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-mouse CD106

E16FMJ106-100U 100 μg
EUR 931.67
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-mouse CD18

E16FMJ018-100U 100 μg
EUR 931.67
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-mouse CD19

E16FMJ019-100U 100 μg
EUR 931.67
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-mouse CD31

E16FMJ031-100U 100 μg
EUR 931.67
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-mouse CD45

E16FMJ045-100U 100 μg
EUR 931.67
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-mouse CD68

E16FMJ068-100U 100 μg
EUR 1365
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-human CD14

E16FHJ0142-100U 100 μg
EUR 975
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-human CD19

E16FHJ019-100U 100 μg
EUR 1083.33
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-mouse CD11c

E16FMJ011c-100U 100 μg
EUR 758.33
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-human CD11a

E16FHJ011a-100U 100 μg
EUR 975
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-human CD11b

E16FHJ011b-100U 100 μg
EUR 931.67
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-mouse CD3

E16FMJ003-100U 100 μg
EUR 931.67
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-mouse CD4

E16FMJ004-100U 100 μg
EUR 931.67
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-human CD3

E16FHJ003-100U 100ug
EUR 975
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-human CD4

E16FHJ004-100U 100 μg
EUR 975
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-mouse CD8a

E16FMJ008a-100U 100 μg
EUR 758.33
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-human CD8a

E16FHJ008a-100U 100 μg
EUR 975
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-mouse CD206 (MMR)

E16FMJ206-100U 100 μg
EUR 1191.67
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-human/mouse CD44

E16FMJ044-100U 100 μg
EUR 931.67
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-human/mouse CD11b

E16FMJ011b-100U 100 μg
EUR 931.67
Description: Available in various conjugation types.

XFD594 Anti-human CD34 Antibody *4H11, XFD594 Same Structure to Alexa Fluorâ„¢ 594*

10340170 100 tests
EUR 250
Description: 4H11 is an anti-human monoclonal antibody that recognizes the CD34 antigen.

XFD594 Anti-human CD34 Antibody *4H11, XFD594 Same Structure to Alexa Fluorâ„¢ 594*

10340171 500 tests
EUR 937
Description: 4H11 is an anti-human monoclonal antibody that recognizes the CD34 antigen.

Anti-Hu CD34 Alexa Fluor® 700

A7-297-T025 25 tests
EUR 121

Anti-Hu CD34 Alexa Fluor® 700

A7-297-T100 100 tests
EUR 242

Anti-Hu CD34 Alexa Fluor® 488

A4-297-T025 25 tests
EUR 121

Anti-Hu CD34 Alexa Fluor® 488

A4-297-T100 100 tests
EUR 242

Alexa Fluor® 594 anti-mouse CD115 (CSF-1R)

E16FMJ115-100U 100 μg
EUR 1061.67
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-mouse CD326 (Ep-CAM)

E16FMJ326-100U 100 μg
EUR 1061.67
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-human CD326 (Ep-CAM)

E16FHJ326-100U 100 μg
EUR 1061.67
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-mouse CD107a (LAMP-1)

E16FMJ107a-100U 100 μg
EUR 931.67
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-human CD324 (E-Cadherin)

E16FHJ324-100U 100 μg
EUR 758.33
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-human CD144 (VE-Cadherin)

E16FHJ144-100U 100 μg
EUR 1191.67
Description: Available in various conjugation types.

Alexa Fluor® 594 anti-human/mouse CD45R/B220

E16FMJ045R-100U 100 μg
EUR 931.67
Description: Available in various conjugation types.

XFD594 Anti-human CD111 Antibody *R1.302, XFD594 Same Structure to Alexa Fluor™ 594*

11110160-100tests 100 tests
EUR 547
Description: R1.302 is an anti-human monoclonal antibody that forms an immune complex with the CD111 antigen.

XFD594 Anti-human CD111 Antibody *R1.302, XFD594 Same Structure to Alexa Fluor™ 594*

11110161-500tests 500 tests
EUR 2051
Description: R1.302 is an anti-human monoclonal antibody that forms an immune complex with the CD111 antigen.

XFD594 Anti-human CD112 Antibody *R2.525, XFD594 Same Structure to Alexa Fluor™ 594*

11120160-100tests 100 tests
EUR 547
Description: R2.525 is an anti-human monoclonal antibody that forms an immune complex with the CD112 antigen.

XFD594 Anti-human CD112 Antibody *R2.525, XFD594 Same Structure to Alexa Fluor™ 594*

11120161-500tests 500 tests
EUR 2051
Description: R2.525 is an anti-human monoclonal antibody that forms an immune complex with the CD112 antigen.

XFD594 Anti-human CD117 Antibody *104D2, XFD594 Same Structure to Alexa Fluor™ 594*

11170170-100tests 100 tests
EUR 547
Description: The 104D2 monoclonal antibody reacts with human CD117, a 145 kD single-pass type i membrane protein typically found on the surface of leukemias, embryonic stem cells, mesenchymal stem cells and mast cells.

XFD594 Anti-human CD117 Antibody *104D2, XFD594 Same Structure to Alexa Fluor™ 594*

11170171-500tests 500 tests
EUR 2051
Description: The 104D2 monoclonal antibody reacts with human CD117, a 145 kD single-pass type i membrane protein typically found on the surface of leukemias, embryonic stem cells, mesenchymal stem cells and mast cells.

XFD594 Anti-human CD133 Antibody *293C3, XFD594 Same Structure to Alexa Fluor™ 594*

11330160-100tests 100 tests
EUR 607
Description: The 293C3 monoclonal antibody recognizes human CD133, a 120 kD transmembrane protein typically located on the surface of epithelials and fetal liver cells.

XFD594 Anti-human CD133 Antibody *293C3, XFD594 Same Structure to Alexa Fluor™ 594*

11330161-500tests 500 tests
EUR 2280
Description: The 293C3 monoclonal antibody recognizes human CD133, a 120 kD transmembrane protein typically located on the surface of epithelials and fetal liver cells.

XFD350 Anti-human CD34 Antibody *4H11, XFD350 Same Structure to Alexa Fluor™ 350*

10340140-100tests 100 tests
EUR 245
Description: 4H11 is an anti-human monoclonal antibody that recognizes the CD34 antigen.

XFD350 Anti-human CD34 Antibody *4H11, XFD350 Same Structure to Alexa Fluor™ 350*

10340141-500tests 500 tests
EUR 918
Description: 4H11 is an anti-human monoclonal antibody that recognizes the CD34 antigen.

XFD488 Anti-human CD34 Antibody *4H11, XFD488 Same Structure to Alexa Fluor™ 488*

10340150-100tests 100 tests
EUR 245
Description: 4H11 is an anti-human monoclonal antibody that recognizes the CD34 antigen.

XFD488 Anti-human CD34 Antibody *4H11, XFD488 Same Structure to Alexa Fluor™ 488*

10340151-500tests 500 tests
EUR 918
Description: 4H11 is an anti-human monoclonal antibody that recognizes the CD34 antigen.

XFD555 Anti-human CD34 Antibody *4H11, XFD555 Same Structure to Alexa Fluor™ 555*

10340160-100tests 100 tests
EUR 245
Description: 4H11 is an anti-human monoclonal antibody that recognizes the CD34 antigen.

XFD555 Anti-human CD34 Antibody *4H11, XFD555 Same Structure to Alexa Fluor™ 555*

10340161-500tests 500 tests
EUR 918
Description: 4H11 is an anti-human monoclonal antibody that recognizes the CD34 antigen.

XFD647 Anti-human CD34 Antibody *4H11, XFD647 Same Structure to Alexa Fluor™ 647*

10340180-100tests 100 tests
EUR 245
Description: 4H11 is an anti-human monoclonal antibody that recognizes the CD34 antigen.

XFD647 Anti-human CD34 Antibody *4H11, XFD647 Same Structure to Alexa Fluor™ 647*

10340181-500tests 500 tests
EUR 918
Description: 4H11 is an anti-human monoclonal antibody that recognizes the CD34 antigen.

XFD680 Anti-human CD34 Antibody *4H11, XFD680 Same Structure to Alexa Fluor™ 680*

10340190-100tests 100 tests
EUR 245
Description: 4H11 is an anti-human monoclonal antibody that recognizes the CD34 antigen.

XFD680 Anti-human CD34 Antibody *4H11, XFD680 Same Structure to Alexa Fluor™ 680*

10340191-500tests 500 tests
EUR 918
Description: 4H11 is an anti-human monoclonal antibody that recognizes the CD34 antigen.

XFD700 Anti-human CD34 Antibody *4H11, XFD700 Same Structure to Alexa Fluor™ 700*

103401A0-100tests 100 tests
EUR 245
Description: 4H11 is an anti-human monoclonal antibody that recognizes the CD34 antigen.

XFD700 Anti-human CD34 Antibody *4H11, XFD700 Same Structure to Alexa Fluor™ 700*

103401A1-500tests 500 tests
EUR 918
Description: 4H11 is an anti-human monoclonal antibody that recognizes the CD34 antigen.

XFD750 Anti-human CD34 Antibody *4H11, XFD750 Same Structure to Alexa Fluor™ 750*

103401B0-100tests 100 tests
EUR 245
Description: 4H11 is an anti-human monoclonal antibody that recognizes the CD34 antigen.

XFD750 Anti-human CD34 Antibody *4H11, XFD750 Same Structure to Alexa Fluor™ 750*

103401B1-500tests 500 tests
EUR 918
Description: 4H11 is an anti-human monoclonal antibody that recognizes the CD34 antigen.

XFD594 Anti-human CD28 Antibody *CD28.2, XFD594 Same Structure to Alexa Fluor™ 594*

10280170-100tests 100 tests
EUR 245
Description: CD28.2 is an anti-human monoclonal antibody that forms an immune complex with the CD28 antigen.

XFD594 Anti-human CD28 Antibody *CD28.2, XFD594 Same Structure to Alexa Fluor™ 594*

10280171-500tests 500 tests
EUR 918
Description: CD28.2 is an anti-human monoclonal antibody that forms an immune complex with the CD28 antigen.

XFD594 Anti-human CD84 Antibody *CD84.1.21, XFD594 Same Structure to Alexa Fluor™ 594*

10840170-100tests 100 tests
EUR 547
Description: CD84.1.21 is an anti-human monoclonal antibody that forms an immune complex with the CD84 antigen.

XFD594 Anti-human CD84 Antibody *CD84.1.21, XFD594 Same Structure to Alexa Fluor™ 594*

10840171-500tests 500 tests
EUR 2051
Description: CD84.1.21 is an anti-human monoclonal antibody that forms an immune complex with the CD84 antigen.

XFD594 Anti-human CD101 Antibody *BB27, XFD594 Same Structure to Alexa Fluor™ 594*

11010160-100tests 100 tests
EUR 547
Description: The BB27 monoclonal antibody binds to human CD101, a 120 kD member of the Ig superfamily commonly found on the surface of T cells, granulocytes and dendritic cells.

XFD594 Anti-human CD101 Antibody *BB27, XFD594 Same Structure to Alexa Fluor™ 594*

11010161-500tests 500 tests
EUR 2051
Description: The BB27 monoclonal antibody binds to human CD101, a 120 kD member of the Ig superfamily commonly found on the surface of T cells, granulocytes and dendritic cells.

XFD594 Anti-human CD314 Antibody *1D11, XFD594 Same Structure to Alexa Fluor™ 594*

13140170-100tests 100 tests
EUR 547
Description: The 1D11 monoclonal antibody binds to human CD314, a transmembrane protein commonly found on the surface of natural killer cells and T cells.

XFD594 Anti-human CD314 Antibody *1D11, XFD594 Same Structure to Alexa Fluor™ 594*

13140171-500tests 500 tests
EUR 2051
Description: The 1D11 monoclonal antibody binds to human CD314, a transmembrane protein commonly found on the surface of natural killer cells and T cells.

XFD594 Anti-human CD318 Antibody *CUB1, XFD594 Same Structure to Alexa Fluor™ 594*

13180170-100tests 100 tests
EUR 547
Description: CUB1 is an anti-human monoclonal antibody that recognizes the CD318 antigen.

XFD594 Anti-human CD318 Antibody *CUB1, XFD594 Same Structure to Alexa Fluor™ 594*

13180171-500tests 500 tests
EUR 2051
Description: CUB1 is an anti-human monoclonal antibody that recognizes the CD318 antigen.

XFD594 Anti-human CD324 Antibody *67A4, XFD594 Same Structure to Alexa Fluor™ 594*

13240170-100tests 100 tests
EUR 547
Description: 67A4 is an anti-human monoclonal antibody that targets the CD324 antigen.

XFD594 Anti-human CD324 Antibody *67A4, XFD594 Same Structure to Alexa Fluor™ 594*

13240171-500tests 500 tests
EUR 2051
Description: 67A4 is an anti-human monoclonal antibody that targets the CD324 antigen.

XFD594 Anti-human CD340 Antibody *24D2, XFD594 Same Structure to Alexa Fluor™ 594*

13400170-100tests 100 tests
EUR 547
Description: 24D2 is an anti-human monoclonal antibody that targets the CD340 antigen.

XFD594 Anti-human CD340 Antibody *24D2, XFD594 Same Structure to Alexa Fluor™ 594*

13400171-500tests 500 tests
EUR 2051
Description: 24D2 is an anti-human monoclonal antibody that targets the CD340 antigen.

XFD594 Anti-human CD267 Antibody *1A1, XFD594 Same Structure to Alexa Fluor™ 594*

12670170-100tests 100 tests
EUR 547
Description: The 1A1 monoclonal antibody binds with human CD267, a 32 kD single-pass type iii membrane protein typically found on the surface of meyloma cells and B cells.

XFD594 Anti-human CD267 Antibody *1A1, XFD594 Same Structure to Alexa Fluor™ 594*

12670171-500tests 500 tests
EUR 2051
Description: The 1A1 monoclonal antibody binds with human CD267, a 32 kD single-pass type iii membrane protein typically found on the surface of meyloma cells and B cells.

XFD594 Anti-human CD268 Antibody *11C1, XFD594 Same Structure to Alexa Fluor™ 594*

12680170-100tests 100 tests
EUR 547
Description: 11C1 is an anti-human monoclonal antibody that forms an immune complex with the CD268 antigen.

XFD594 Anti-human CD268 Antibody *11C1, XFD594 Same Structure to Alexa Fluor™ 594*

12680171-500tests 500 tests
EUR 2051
Description: 11C1 is an anti-human monoclonal antibody that forms an immune complex with the CD268 antigen.

XFD594 Anti-human CD279 Antibody *3D1, XFD594 Same Structure to Alexa Fluor™ 594*

12790160-100tests 100 tests
EUR 245
Description: The 3D1 monoclonal antibody reacts with human CD279, a 50 - 55 kD member of the Ig superfamily typically located on the surface of t cells and b cells.

XFD594 Anti-human CD279 Antibody *3D1, XFD594 Same Structure to Alexa Fluor™ 594*

12790161-500tests 500 tests
EUR 918
Description: The 3D1 monoclonal antibody reacts with human CD279, a 50 - 55 kD member of the Ig superfamily typically located on the surface of t cells and b cells.

XFD594 Anti-human CD279 Antibody *2E7, XFD594 Same Structure to Alexa Fluor™ 594*

12791170-100tests 100 tests
EUR 245
Description: 2E7 is an anti-human monoclonal antibody that targets the CD279 antigen.

XFD594 Anti-human CD279 Antibody *2E7, XFD594 Same Structure to Alexa Fluor™ 594*

12791171-500tests 500 tests
EUR 918
Description: 2E7 is an anti-human monoclonal antibody that targets the CD279 antigen.

XFD594 Anti-human CD279 Antibody *J110, XFD594 Same Structure to Alexa Fluor™ 594*

12792170-100tests 100 tests
EUR 245
Description: J110 is an anti-human monoclonal antibody that targets the CD279 antigen.

XFD594 Anti-human CD279 Antibody *J110, XFD594 Same Structure to Alexa Fluor™ 594*

12792171-500tests 500 tests
EUR 918
Description: J110 is an anti-human monoclonal antibody that targets the CD279 antigen.

XFD594 Anti-human CD279 Antibody *J116, XFD594 Same Structure to Alexa Fluor™ 594*

12793170-100tests 100 tests
EUR 245
Description: The J116 monoclonal antibody binds to human CD279, a 50 - 55 kD member of the Ig superfamily commonly located on the surface of B cells and thymocytes.

XFD594 Anti-human CD279 Antibody *J116, XFD594 Same Structure to Alexa Fluor™ 594*

12793171-500tests 500 tests
EUR 918
Description: The J116 monoclonal antibody binds to human CD279, a 50 - 55 kD member of the Ig superfamily commonly located on the surface of B cells and thymocytes.

XFD594 Anti-human CD122 Antibody *TU27, XFD594 Same Structure to Alexa Fluor™ 594*

11220160-100tests 100 tests
EUR 547
Description: TU27 is an anti-human monoclonal antibody that is specific for the CD122 antigen.

XFD594 Anti-human CD122 Antibody *TU27, XFD594 Same Structure to Alexa Fluor™ 594*

11220161-500tests 500 tests
EUR 2051
Description: TU27 is an anti-human monoclonal antibody that is specific for the CD122 antigen.

XFD594 Anti-human CD123 Antibody *6H6, XFD594 Same Structure to Alexa Fluor™ 594*

11230170-100tests 100 tests
EUR 157
Description: The 6H6 monoclonal antibody reacts with human CD123, a 70 kD member of the Ig superfamily frequently expressed on the surface of megakaryocytes and macrophages.

XFD594 Anti-human CD123 Antibody *6H6, XFD594 Same Structure to Alexa Fluor™ 594*

11230171-500tests 500 tests
EUR 484
Description: The 6H6 monoclonal antibody reacts with human CD123, a 70 kD member of the Ig superfamily frequently expressed on the surface of megakaryocytes and macrophages.

XFD594 Anti-human CD123 Antibody *12H7, XFD594 Same Structure to Alexa Fluor™ 594*

11231160-100tests 100 tests
EUR 245
Description: The 12H7 monoclonal antibody binds to human CD123, a 70 kD single-pass type I membrane protein often located on the surface of macrophages, hematopoietic progenitors and dendritic cells.

XFD594 Anti-human CD123 Antibody *12H7, XFD594 Same Structure to Alexa Fluor™ 594*

11231161-500tests 500 tests
EUR 918
Description: The 12H7 monoclonal antibody binds to human CD123, a 70 kD single-pass type I membrane protein often located on the surface of macrophages, hematopoietic progenitors and dendritic cells.

XFD594 Anti-human CD109 Antibody *W7C5, XFD594 Same Structure to Alexa Fluor™ 594*

11090160-100tests 100 tests
EUR 547
Description: The W7C5 monoclonal antibody binds with human CD109, a 162 kD transmembrane protein typically expressed on the surface of T cells and T cell lines.

XFD594 Anti-human CD109 Antibody *W7C5, XFD594 Same Structure to Alexa Fluor™ 594*

11090161-500tests 500 tests
EUR 2051
Description: The W7C5 monoclonal antibody binds with human CD109, a 162 kD transmembrane protein typically expressed on the surface of T cells and T cell lines.

XFD594 Anti-human CD116 Antibody *4H1, XFD594 Same Structure to Alexa Fluor™ 594*

11160160-100tests 100 tests
EUR 547
Description: The 4H1 monoclonal antibody binds to human CD116, a 70 - 85 kD glycoprotein commonly located on the surface of endothelial precursors and macrophages.

XFD594 Anti-human CD116 Antibody *4H1, XFD594 Same Structure to Alexa Fluor™ 594*

11160161-500tests 500 tests
EUR 2051
Description: The 4H1 monoclonal antibody binds to human CD116, a 70 - 85 kD glycoprotein commonly located on the surface of endothelial precursors and macrophages.

XFD594 Anti-human CD138 Antibody *MI15, XFD594 Same Structure to Alexa Fluor™ 594*

11380170-100tests 100 tests
EUR 245
Description: The MI15 monoclonal antibody reacts with human CD138, a 100 - 200 kD transmembrane protein typically expressed on the surface of b cells, plasma cells, epithelial cells and endothelial cells.

XFD594 Anti-human CD138 Antibody *MI15, XFD594 Same Structure to Alexa Fluor™ 594*

11380171-500tests 500 tests
EUR 918
Description: The MI15 monoclonal antibody reacts with human CD138, a 100 - 200 kD transmembrane protein typically expressed on the surface of b cells, plasma cells, epithelial cells and endothelial cells.

XFD594 Anti-human CD107 Antibody *H4B4, XFD594 Same Structure to Alexa Fluor™ 594*

11071160-100tests 100 tests
EUR 547
Description: H4B4 is an anti-human monoclonal antibody that targets the CD107b antigen.

XFD594 Anti-human CD107 Antibody *H4B4, XFD594 Same Structure to Alexa Fluor™ 594*

11071161-500tests 500 tests
EUR 2051
Description: H4B4 is an anti-human monoclonal antibody that targets the CD107b antigen.

XFD594 Anti-human CD205 Antibody *HD30, XFD594 Same Structure to Alexa Fluor™ 594*

12050160-100tests 100 tests
EUR 547
Description: HD30 is an anti-human monoclonal antibody that targets the CD205 antigen.

XFD594 Anti-human CD205 Antibody *HD30, XFD594 Same Structure to Alexa Fluor™ 594*

12050161-500tests 500 tests
EUR 2051
Description: HD30 is an anti-human monoclonal antibody that targets the CD205 antigen.

XFD594 Anti-human CD209 Antibody *UW60.1, XFD594 Same Structure to Alexa Fluor™ 594*

12090170-100tests 100 tests
EUR 547
Description: UW60.1 is an anti-human monoclonal antibody that targets the CD209 antigen.

XFD594 Anti-human CD209 Antibody *UW60.1, XFD594 Same Structure to Alexa Fluor™ 594*

12090171-500tests 500 tests
EUR 2051
Description: UW60.1 is an anti-human monoclonal antibody that targets the CD209 antigen.

XFD594 Anti-human CD229 Antibody *HLy9.25, XFD594 Same Structure to Alexa Fluor™ 594*

12290170-100tests 100 tests
EUR 547
Description: The HLy9.25 monoclonal antibody reacts with human CD229, a 100 - 120 kD transmembrane protein frequently found on the surface of thymocytes, B cells, T cells and natural killer cells.

XFD594 Anti-human CD229 Antibody *HLy9.25, XFD594 Same Structure to Alexa Fluor™ 594*

12290171-500tests 500 tests
EUR 2051
Description: The HLy9.25 monoclonal antibody reacts with human CD229, a 100 - 120 kD transmembrane protein frequently found on the surface of thymocytes, B cells, T cells and natural killer cells.

XFD594 Anti-human CD231 Antibody *B2D, XFD594 Same Structure to Alexa Fluor™ 594*

12310170-100tests 100 tests
EUR 547
Description: The B2D monoclonal antibody binds with human CD231, a transmembrane protein frequently found on the surface of skeletal muscles, neurons, spleens and leukemias.

XFD594 Anti-human CD231 Antibody *B2D, XFD594 Same Structure to Alexa Fluor™ 594*

12310171-500tests 500 tests
EUR 2051
Description: The B2D monoclonal antibody binds with human CD231, a transmembrane protein frequently found on the surface of skeletal muscles, neurons, spleens and leukemias.

XFD594 Anti-human CD235 Antibody *HIR2, XFD594 Same Structure to Alexa Fluor™ 594*

12351170-100tests 100 tests
EUR 245
Description: HIR2 is an anti-human monoclonal antibody that targets the CD235a antigen.

XFD594 Anti-human CD235 Antibody *HIR2, XFD594 Same Structure to Alexa Fluor™ 594*

12351171-500tests 500 tests
EUR 918
Description: HIR2 is an anti-human monoclonal antibody that targets the CD235a antigen.

XFD594 Anti-human CD243 Antibody *UIC2, XFD594 Same Structure to Alexa Fluor™ 594*

12430170-100tests 100 tests
EUR 547
Description: The UIC2 monoclonal antibody recognizes human CD243, a 170 kD member of the Member of ABC transporter family typically located on the surface of hematopoietic stem cells, T cells, natural killer cells and B cells.

XFD594 Anti-human CD243 Antibody *UIC2, XFD594 Same Structure to Alexa Fluor™ 594*

12430171-500tests 500 tests
EUR 2051
Description: The UIC2 monoclonal antibody recognizes human CD243, a 170 kD member of the Member of ABC transporter family typically located on the surface of hematopoietic stem cells, T cells, natural killer cells and B cells.

XFD594 Anti-human CD253 Antibody *2E5, XFD594 Same Structure to Alexa Fluor™ 594*

12530170-100tests 100 tests
EUR 547
Description: 2E5 is an anti-human monoclonal antibody that recognizes the CD253 antigen.

XFD594 Anti-human CD253 Antibody *2E5, XFD594 Same Structure to Alexa Fluor™ 594*

12530171-500tests 500 tests
EUR 2051
Description: 2E5 is an anti-human monoclonal antibody that recognizes the CD253 antigen.

XFD594 Anti-human CD152 Antibody *BN13, XFD594 Same Structure to Alexa Fluor™ 594*

11520170-100tests 100 tests
EUR 245
Description: The BN13 monoclonal antibody binds to human CD152, a 33 kD transmembrane protein frequently expressed on the surface of B cells and T cells.

XFD594 Anti-human CD152 Antibody *BN13, XFD594 Same Structure to Alexa Fluor™ 594*

11520171-500tests 500 tests
EUR 918
Description: The BN13 monoclonal antibody binds to human CD152, a 33 kD transmembrane protein frequently expressed on the surface of B cells and T cells.

XFD594 Anti-human CD160 Antibody *BY55, XFD594 Same Structure to Alexa Fluor™ 594*

11600160-100tests 100 tests
EUR 547
Description: The BY55 monoclonal antibody recognizes human CD160, a 27 kD transmembrane protein typically located on the surface of natural killer cells and T cells.

XFD594 Anti-human CD160 Antibody *BY55, XFD594 Same Structure to Alexa Fluor™ 594*

11600161-500tests 500 tests
EUR 2051
Description: The BY55 monoclonal antibody recognizes human CD160, a 27 kD transmembrane protein typically located on the surface of natural killer cells and T cells.

XFD594 Anti-human CD162 Antibody *TC2, XFD594 Same Structure to Alexa Fluor™ 594*

11620160-100tests 100 tests
EUR 547
Description: TC2 is an anti-human monoclonal antibody that forms an immune complex with the CD162 antigen.

XFD594 Anti-human CD162 Antibody *TC2, XFD594 Same Structure to Alexa Fluor™ 594*

11620161-500tests 500 tests
EUR 2051
Description: TC2 is an anti-human monoclonal antibody that forms an immune complex with the CD162 antigen.

XFD594 Anti-human CD164 Antibody *67D2, XFD594 Same Structure to Alexa Fluor™ 594*

11640160-100tests 100 tests
EUR 547
Description: The 67D2 monoclonal antibody binds with human CD164, a transmembrane glycoprotein typically found on the surface of leukemias, ls and basophils.

XFD594 Anti-human CD164 Antibody *67D2, XFD594 Same Structure to Alexa Fluor™ 594*

11640161-500tests 500 tests
EUR 2051
Description: The 67D2 monoclonal antibody binds with human CD164, a transmembrane glycoprotein typically found on the surface of leukemias, ls and basophils.

XFD594 Anti-human CD165 Antibody *SN2, XFD594 Same Structure to Alexa Fluor™ 594*

11650160-100tests 100 tests
EUR 547
Description: The SN2 monoclonal antibody recognizes human CD165, a glycoprotein typically expressed on the surface of monocytes, fibroblasts, T cells and thymocytes.

XFD594 Anti-human CD165 Antibody *SN2, XFD594 Same Structure to Alexa Fluor™ 594*

11650161-500tests 500 tests
EUR 2051
Description: The SN2 monoclonal antibody recognizes human CD165, a glycoprotein typically expressed on the surface of monocytes, fibroblasts, T cells and thymocytes.

XFD594 Anti-human CD193 Antibody *5E8, XFD594 Same Structure to Alexa Fluor™ 594*

11930160-100tests 100 tests
EUR 547
Description: The 5E8 monoclonal antibody reacts with human CD193, a transmembrane protein typically found on the surface of mononuclear phagocytes and platelets.

XFD594 Anti-human CD193 Antibody *5E8, XFD594 Same Structure to Alexa Fluor™ 594*

11930161-500tests 500 tests
EUR 2051
Description: The 5E8 monoclonal antibody reacts with human CD193, a transmembrane protein typically found on the surface of mononuclear phagocytes and platelets.

XFD594 Anti-mouse CD197 Antibody *4B12, XFD594 Same Structure to Alexa Fluor™ 594*

11970160-100tests 100 tests
EUR 547
Description: 4B12 is an anti-mouse monoclonal antibody that is specific for the CD197 antigen.

XFD594 Anti-mouse CD197 Antibody *4B12, XFD594 Same Structure to Alexa Fluor™ 594*

11970161-500tests 500 tests
EUR 2051
Description: 4B12 is an anti-mouse monoclonal antibody that is specific for the CD197 antigen.

XFD594 Anti-human CD172 Antibody *B4B6, XFD594 Same Structure to Alexa Fluor™ 594*

11721160-100tests 100 tests
EUR 547
Description: The B4B6 monoclonal antibody binds to human CD172b, a 43 kD transmembrane protein often located on the surface of dendritic cells, myeloid cells and monocytes.

XFD594 Anti-human CD172 Antibody *B4B6, XFD594 Same Structure to Alexa Fluor™ 594*

11721161-500tests 500 tests
EUR 2051
Description: The B4B6 monoclonal antibody binds to human CD172b, a 43 kD transmembrane protein often located on the surface of dendritic cells, myeloid cells and monocytes.

XFD594 Anti-human CD28 Antibody *9.3, XFD594 Same Structure to Alexa Fluor™ 594*

10281170-100tests 100 tests
EUR 245
Description: The 9.3 monoclonal antibody binds with human CD28, a 44 kD transmembrane glycoprotein typically located on the surface of natural killer cells and plasma cells.

XFD594 Anti-human CD28 Antibody *9.3, XFD594 Same Structure to Alexa Fluor™ 594*

10281171-500tests 500 tests
EUR 918
Description: The 9.3 monoclonal antibody binds with human CD28, a 44 kD transmembrane glycoprotein typically located on the surface of natural killer cells and plasma cells.

XFD594 Anti-human CD64 Antibody *10.1, XFD594 Same Structure to Alexa Fluor™ 594*

10640170-100tests 100 tests
EUR 245
Description: The 10.1 monoclonal antibody binds with human CD64, a 72 kD single-pass type i membrane protein typically expressed on the surface of granulocytes, monocytes and dendritic cells.

XFD594 Anti-human CD64 Antibody *10.1, XFD594 Same Structure to Alexa Fluor™ 594*

10640171-500tests 500 tests
EUR 918
Description: The 10.1 monoclonal antibody binds with human CD64, a 72 kD single-pass type i membrane protein typically expressed on the surface of granulocytes, monocytes and dendritic cells.

XFD594 Anti-human CD32 Antibody *3D3, XFD594 Same Structure to Alexa Fluor™ 594*

10321170-100tests 100 tests
EUR 547
Description: The 3D3 monoclonal antibody binds to human CD32, a 40 kD member of the Ig superfamily often located on the surface of platelets, monocytes, B cells, granulocytes and dendritic cells.

XFD594 Anti-human CD32 Antibody *3D3, XFD594 Same Structure to Alexa Fluor™ 594*

10321171-500tests 500 tests
EUR 2051
Description: The 3D3 monoclonal antibody binds to human CD32, a 40 kD member of the Ig superfamily often located on the surface of platelets, monocytes, B cells, granulocytes and dendritic cells.

XFD594 Anti-human CD16 Antibody *3G8, XFD594 Same Structure to Alexa Fluor™ 594*

10161170-100tests 100 tests
EUR 245
Description: The 3G8 monoclonal antibody recognizes human CD16a, a 50 - 65 kD transmembrane protein typically found on the surface of macrophages, natural killer cells, dendritic cells, monocytes and neutrophils.

XFD594 Anti-human CD16 Antibody *3G8, XFD594 Same Structure to Alexa Fluor™ 594*

10161171-500tests 500 tests
EUR 918
Description: The 3G8 monoclonal antibody recognizes human CD16a, a 50 - 65 kD transmembrane protein typically found on the surface of macrophages, natural killer cells, dendritic cells, monocytes and neutrophils.

XFD594 Anti-human CD19 Antibody *4G7, XFD594 Same Structure to Alexa Fluor™ 594*

10193170-100tests 100 tests
EUR 245
Description: The 4G7 monoclonal antibody binds with human CD19, a 95 kD transmembrane protein commonly expressed on the surface of B cells and lymphocytes.

XFD594 Anti-human CD19 Antibody *4G7, XFD594 Same Structure to Alexa Fluor™ 594*

10193171-500tests 500 tests
EUR 918
Description: The 4G7 monoclonal antibody binds with human CD19, a 95 kD transmembrane protein commonly expressed on the surface of B cells and lymphocytes.

XFD594 Anti-mouse CD19 Antibody *1D3, XFD594 Same Structure to Alexa Fluor™ 594*

10194160-100tests 100 tests
EUR 245
Description: 1D3 is an anti-mouse monoclonal antibody that is specific for the CD19 antigen.

XFD594 Anti-mouse CD19 Antibody *1D3, XFD594 Same Structure to Alexa Fluor™ 594*

10194161-500tests 500 tests
EUR 918
Description: 1D3 is an anti-mouse monoclonal antibody that is specific for the CD19 antigen.

XFD594 Anti-human CD45 Antibody *2D1, XFD594 Same Structure to Alexa Fluor™ 594*

10454170-100tests 100 tests
EUR 245
Description: 2D1 is an anti-human monoclonal antibody that recognizes the CD45 antigen.

XFD594 Anti-human CD45 Antibody *2D1, XFD594 Same Structure to Alexa Fluor™ 594*

10454171-500tests 500 tests
EUR 918
Description: 2D1 is an anti-human monoclonal antibody that recognizes the CD45 antigen.

XFD594 Anti-human CD38 Antibody *HB7, XFD594 Same Structure to Alexa Fluor™ 594*

10382160-100tests 100 tests
EUR 245
Description: HB7 is an anti-human monoclonal antibody that recognizes the CD38 antigen.

XFD594 Anti-human CD38 Antibody *HB7, XFD594 Same Structure to Alexa Fluor™ 594*

10382161-500tests 500 tests
EUR 918
Description: HB7 is an anti-human monoclonal antibody that recognizes the CD38 antigen.

XFD594 Anti-human CD40 Antibody *G28.5, XFD594 Same Structure to Alexa Fluor™ 594*

10401170-100tests 100 tests
EUR 245
Description: G28.5 is an anti-human monoclonal antibody that targets the CD40 antigen.

XFD594 Anti-human CD40 Antibody *G28.5, XFD594 Same Structure to Alexa Fluor™ 594*

10401171-500tests 500 tests
EUR 918
Description: G28.5 is an anti-human monoclonal antibody that targets the CD40 antigen.

XFD594 Anti-human CD72 Antibody *3F3, XFD594 Same Structure to Alexa Fluor™ 594*

10720170-100tests 100 tests
EUR 547
Description: The 3F3 monoclonal antibody binds with human CD72, a 39 - 43 kD transmembrane glycoprotein often located on the surface of B cells, dendritic cells, liver kupffer cells and macrophages.

XFD594 Anti-human CD72 Antibody *3F3, XFD594 Same Structure to Alexa Fluor™ 594*

10720171-500tests 500 tests
EUR 2051
Description: The 3F3 monoclonal antibody binds with human CD72, a 39 - 43 kD transmembrane glycoprotein often located on the surface of B cells, dendritic cells, liver kupffer cells and macrophages.

XFD594 Anti-human CD73 Antibody *AD2, XFD594 Same Structure to Alexa Fluor™ 594*

10730170-100tests 100 tests
EUR 547
Description: AD2 is an anti-human monoclonal antibody that is specific for the CD73 antigen.

Dodaj komentarz

Twój adres e-mail nie zostanie opublikowany. Wymagane pola są oznaczone *